PET scans could guide smarter breast cancer therapy
NCT ID NCT07527806
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a special PET scan (HER2-PET) can help doctors personalize treatment for early-stage HER2-positive breast cancer. After two cycles of standard therapy, the scan results will determine if patients need stronger or milder treatment. The goal is to improve the chance of eliminating the cancer before surgery while avoiding unnecessary side effects. About 156 participants will be enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Trastuzumab, Pertuzumab, Docetaxel, Nab-paclitaxel, Carboplatin, CDK4/6 inhibitor
What this could lead to
If successful, this could lead to a more personalized treatment approach for HER2-positive breast cancer, potentially improving cure rates and reducing unnecessary side effects.
What could go wrong
This is a Phase 2 trial with only 156 participants, so results may not apply to all patients. The imaging technique is experimental, and the treatment adjustments may not improve outcomes or could cause unexpected side effects.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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