Lung cancer drug dose doubled for stubborn tumors in new trial

NCT ID NCT07298148

First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tests whether a higher dose (160 mg) of the targeted drug firmonertinib can shrink or control advanced EGFR-mutant lung cancer in people whose tumors stayed stable after 8 weeks on the standard 80 mg dose. About 28 adults with stage IV non-small cell lung cancer and no prior treatment will take the higher dose once daily. The goal is to see if the stronger dose improves response rates and delays cancer growth.

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