New scan may reveal who will benefit from immunotherapy

NCT ID NCT03564197

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a new type of PET scan, which looks for a protein called PD-L1 on cancer cells, can predict how well patients with advanced lung cancer will respond to the immunotherapy drug nivolumab. Eighty patients received the scan before starting treatment. Researchers then tracked how long their cancer was controlled. The goal is to see if this imaging tool can help personalize treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-PD-L1 PET/CT scan (imaging tracer)

What this could lead to

If successful, this scan could help doctors identify which lung cancer patients are most likely to respond to immunotherapy, avoiding ineffective treatments.

What could go wrong

This is an early imaging study, not a treatment trial. The scan's accuracy may not be high enough to change clinical practice, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Antoni van Leeuwenhoek

    Amsterdam, 1060CX, Netherlands

  • Antonius Ziekenhuis

    Utrecht, Netherlands

  • Deventer Ziekenhuis

    Deventer, Netherlands

  • Jeroen Bosch Ziekenhuis

    's-Hertogenbosch, Netherlands

  • LUMC

    Leiden, Netherlands

  • MeanderMC

    Amersfoort, Netherlands

  • Medisch Centrum Haaglanden

    The Hague, Netherlands

  • VUmc

    Amsterdam, 1007 MB, Netherlands