Blood test could guide lung cancer treatment without invasive biopsies

NCT ID NCT04223596

First seen Feb 04, 2026 · Last updated May 13, 2026 · Updated 19 times

Summary

This study looks at whether a simple blood test (liquid biopsy) can help doctors monitor how well the drug brigatinib is working in people with a specific type of advanced lung cancer (ALK-positive non-small cell lung cancer). About 33 patients who have not had chemotherapy before will take brigatinib pills daily until their cancer worsens or side effects become too much. The main goal is to see how many patients' tumors shrink, and the blood test results will be compared to standard scans to see if it's a reliable way to track the cancer over time.

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Contacts and locations

Locations

  • Complejo Hospitalario de A Coruña

    A Coruña, A Coruña, 15006, Spain

  • Hospital Clínico de Salamanca

    Salamanca, Salamanca, 37007, Spain

  • Hospital General de Alicante

    Alicante, Alicante, 03010, Spain

  • Hospital General de Valencia

    Valencia, Valencia, 46014, Spain

  • Hospital Puerta de Hierro

    Madrid, Madrid, 28222, Spain

  • Hospital Regional Universitario de Málaga

    Málaga, Andalusia, 29010, Spain

  • Hospital Son Espases

    Palma de Mallorca, Balearic Islands, 07120, Spain

  • Hospital Universitari i Politécnic La Fe

    Valencia, Valencia, 46009, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, Madrid, 28040, Spain

  • Hospital Universitario Insular de Gran canaria

    Las Palmas de Gran Canaria, Gran Canaria, 35016, Spain

  • Hospital Universitario de Cruces

    Barakaldo, Vizcaya, 48903, Spain

  • Hospital Vall Hebron

    Barcelona, 08035, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Catalonia, 08041, Spain

  • ICO Badalona

    Badalona, Barcelona, 08916, Spain

  • ICO Hospitalet

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

Conditions

Explore the condition pages connected to this study.