Immunotherapy may let some GI cancer patients skip the knife

This study looks at whether immunotherapy can shrink certain gastrointestinal cancers (like colorectal or stomach cancer) enough that some patients may not need major surgery. People whose tumors have specific genetic features (MSI-H/dMMR or POLE mutation) and who respond well to immunotherapy may be able to simply watch and wait or have a minor procedure instead of a radical operation. The goal is to see if this approach can preserve organ function and avoid permanent colostomy while keeping the cancer under control.