New model could spot dangerous surgical leaks before they happen

NCT ID NCT07709923

Completed Knowledge-focused Sponsor: University of Foggia Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study aims to create a simple model that uses routine clinical and lab data from the first day after colorectal cancer surgery to predict the risk of anastomotic leakage—a serious complication where the surgical connection leaks. Researchers reviewed records of 117 patients who had colorectal cancer surgery with a primary anastomosis. The goal is to help doctors identify high-risk patients early and potentially prevent severe outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this model could help surgeons identify patients at high risk of anastomotic leakage early, potentially reducing severe complications.
What could go wrong: This is a small, retrospective pilot study. The model needs validation in larger, prospective trials before it can be used in practice.

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Conditions

The condition(s) this trial relates to.

Anastomotic Leak colonic neoplasm colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL (COLON OR RECTAL) CANCER LEAK, ANASTOMOTIC SURGERY COMPLICATIONS

Contacts and locations

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Locations

Giovanna Pavone

Foggia, 71122, Italy

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