Brain damage markers tracked during robotic prostate surgery

NCT ID NCT05692804

Completed Knowledge-focused Sponsor: Akdeniz University Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study looks at whether the steep head-down position used during robot-assisted prostate surgery can cause subtle brain injury. Researchers measure three brain-specific proteins (S100B, GFAP, and NSE) in the blood before and after surgery, along with simple cognitive tests. The goal is to see if these markers rise, signaling possible brain stress or damage. About 59 adults undergoing robotic prostate removal will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Measurement of S100B, GFAP, and NSE biomarkers in blood, plus cognitive tests (MMSE, MoCA)
What this could lead to: If brain damage markers rise during robotic prostate surgery, it could lead to safer positioning guidelines to protect patients' brains.
What could go wrong: This is a small, early study measuring temporary chemical changes, not actual brain injury. The markers may not reflect real harm.

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Conditions

The condition(s) this trial relates to.

brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN DAMAGE POSTOPERATIVE SURGERY COMPLICATIONS

Contacts and locations

Locations

Akdeniz University Hospital

Antalya, 07070, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.