New hope for hard-to-treat breast cancer: experimental drug takes on standard therapy

NCT ID NCT07417241

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new drug, SHR-A1811, with a standard combination therapy (pyrotinib plus capecitabine) in 100 adults with advanced HER2-positive breast cancer that did not respond to the first-line treatment trastuzumab. The goal is to see which approach better delays cancer growth. Participants will be randomly assigned to one of the two treatments and monitored for side effects and progression-free survival.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••