New drug cocktail aims to stop Chemo-Linked nausea before it starts
NCT ID NCT07692451
First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study tests whether a combination of two drugs, fosrolapitant and palonosetron, can prevent nausea and vomiting caused by antibody-drug conjugates (ADCs) in cancer patients. Participants are adults with malignant tumors who have never received ADCs before and are about to start their first course. The trial compares the experimental drug combo against a standard treatment to see which better achieves a complete response (no vomiting and no need for rescue medication).
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fosrolapitant and Palonosetron for injection
- What this could lead to
- If successful, this could provide a new option to prevent nausea and vomiting in cancer patients receiving antibody-drug conjugates, improving treatment tolerability.
- What could go wrong
- This is a Phase 2 trial with a moderate number of participants, so results are preliminary. The drug may not prove more effective than existing treatments, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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