Nyu Langone Health

This study tests a precise radiation technique called VMAT for people with solid tumors that have spread to the lining of the brain and spine (leptomeningeal metastasis). The goal is to see if this approach can delay cancer progression in the central nervous system better than st…

This study tests whether a collaborative care model—where primary care doctors work with a care team—can help adults reduce their use of opioids, stimulants (like cocaine or meth), and heavy alcohol. About 300 participants will receive this team-based support. The goal is to see …

This study tests a program where HIV nurses are trained to also manage high blood pressure in patients living with HIV in Nigeria. The goal is to see if this approach helps lower blood pressure over 12 months. The study involves 830 adults with both HIV and uncontrolled high bloo…

This study tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy and radiation can help control muscle-invasive bladder cancer while allowing patients to keep their bladder. It involves 60 adults who are not candidates for or choose not to have bladde…

This study tests whether a telehealth coaching program led by community health workers can help South Asian patients with type 2 diabetes and high blood pressure better control their conditions. About 450 adults will either receive the coaching or usual care. The main goal is to …

This study tests whether keeping people with opioid use disorder in the emergency department for a longer observation period helps them start medication like buprenorphine and connect to follow-up care. About 170 adults from four hospitals will be randomly assigned to standard ER…

This study tests a new, faster breast MRI technique called GRASP that takes only a few minutes. Researchers want to see if it can tell the difference between harmless and cancerous breast lumps by measuring how contrast dye flows in. About 264 women already scheduled for a standa…

This study tests whether a structured diet, exercise, and lifestyle program can help prevent uterine fibroids from coming back after they have been surgically removed. About 100 women aged 18-50 who are fibroid-free after surgery will follow the program for several months. Resear…

This study tests if a shorter course of radiation (3 treatments over 5 days) is as safe and effective as the standard 5-day course for women with early-stage breast cancer. About 284 post-menopausal women with small, low-risk tumors took part. The goal is to see if the shorter sc…

This small pilot study tests whether a dissolvable film containing dexmedetomidine can be used at home to treat sudden, severe episodes (autonomic crises) in people with familial dysautonomia, a rare nerve disorder. Five adults who have had these crises before will receive the fi…

This study looks at a new way to help older adults with hearing loss who may not have easy access to hearing care. During a regular doctor visit, participants will be screened for hearing loss and then randomly assigned to either get counseling on affordable listening devices or …

This study tests a medicated film placed under the tongue to quickly calm severe episodes (autonomic crises) in people with familial dysautonomia, a rare nerve disorder. About 15 participants aged 16+ will receive either the drug or a placebo at home. The goal is to see if the fi…

This study tests a new technique that stimulates the entire cochlea using standard-length electrodes, potentially improving speech understanding and sound quality for people with cochlear implants. Researchers will enroll 40 adults who already qualify for a cochlear implant. The …

This study looks at 15 people who had a heart attack but whose arteries were not blocked. Researchers use special cameras to see inside the arteries and the heart muscle. The goal is to learn what causes these heart attacks, not to test a new treatment.

This study looks at people who had a heart attack but no blocked arteries (MINOCA). Researchers use special imaging to find the real cause, like plaque disruption or artery tears. 450 participants will be followed for up to 10 years to track future health events.

This study looks at how age-related sleep changes and sleep apnea may increase the risk of Alzheimer's disease in healthy older adults. Researchers will monitor sleep patterns and brain amyloid buildup in 158 people aged 55-75 over two years. The goal is to understand how sleep p…

This study looks at whether sending cardiologists quarterly emails about their prescribing habits can improve care for people with heart failure or atrial fibrillation. Researchers will track if more patients get the recommended medications. About 7,000 adults from one health sys…

This study tests whether advanced MRI scans can predict the type of kidney cancer and how well the kidney will work after surgery. About 39 adults scheduled for partial kidney removal will have special MRI scans before their operation. The goal is to see if these scans can help d…

This study looks at why some women with heart disease symptoms have clear major arteries but still experience chest pain. Researchers think tiny blood vessels in the heart may not work properly due to inflammation or blood cell activity. About 206 women will be observed during a …

This study looks at 200 FDNY rescue workers who were exposed to toxins at the World Trade Center site. Many have developed acid reflux, Barrett's esophagus, or airway disease. Researchers will test saliva and breath samples and use questionnaires to find better, noninvasive ways …

This pilot study tests a community-based educational program to raise awareness of melanoma and other skin cancers. About 45 adults in Brooklyn will attend a session led by a health worker and complete surveys and follow-ups over 12 months. The goal is to see if the program impro…

This study tests whether an automatic reminder in the medical record helps doctors order liver ultrasounds for people with cirrhosis. About 1,300 adults with cirrhosis who haven't had recent imaging will be included. The goal is to see if this simple nudge increases screening and…