New Bladder-Sparing cocktail shows promise for tough cancer

NCT ID NCT02621151

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 23 times

Summary

This study tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy and radiation can help control muscle-invasive bladder cancer while allowing patients to keep their bladder. It involves 60 adults who are not candidates for or choose not to have bladder removal surgery. The main goal is to see how many remain cancer-free in the bladder after two years.

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Contacts and locations

Locations

  • Memorial Sloan Kettering

    New York, New York, 10065, United States

  • NYU Perlmutter Cancer Center

    New York, New York, 10016, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599-7305, United States

Conditions

Explore the condition pages connected to this study.