New dissolving film may stop dangerous episodes in rare nerve disease

NCT ID NCT06148311

First seen Apr 14, 2026 · Last updated Jun 18, 2026 · Updated 15 times

Summary

This study tests a medicated film placed under the tongue to quickly ease severe episodes (autonomic crises) in people with familial dysautonomia. The film contains dexmedetomidine, a drug that calms the body's stress response. Researchers will check if it reduces symptoms like high blood pressure, rapid heart rate, and vomiting. The study involves 15 people aged 16 and older who have had at least one crisis in the past year.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FAMILIAL DYSAUTONOMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

Conditions

The condition(s) this trial relates to.

hereditary sensory and autonomic neuropathy Riley-Day syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.