New radiation approach aims to slow cancer in the brain and spine

NCT ID NCT06984523

First seen Apr 09, 2026 · Last updated Jun 20, 2026 · Updated 9 times

Summary

This study tests a precise type of radiation called VMAT for people whose cancer has spread to the lining of the brain and spine (leptomeningeal metastasis). The goal is to see if this approach can delay cancer growth in the central nervous system better than older radiation methods. Twenty adults with solid tumors will receive 10 sessions of targeted radiation. Researchers will track how long patients go without their cancer worsening in the brain or spine.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (VMAT craniospinal irradiation)

What this could lead to

If successful, this could offer a more effective radiation option for people with cancer spread to the brain and spine lining, potentially delaying disease progression.

What could go wrong

This is a small, early-phase study with only 20 participants and no comparison group. The results may not apply to all patients, and radiation can cause side effects like fatigue or neurological symptoms.

Conditions

The condition(s) this trial relates to.

Meningeal Carcinomatosis neoplastic meningitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.