Sound waves aimed at brain may quiet schizophrenia symptoms
NCT ID NCT05259306
First seen Apr 07, 2026 · Last updated Jun 23, 2026 · Updated 12 times
Summary
This small pilot study tests whether low-intensity focused ultrasound, guided by MRI, can safely and precisely target a deep brain region called the thalamus in people with treatment-resistant schizophrenia. The goal is to see if this noninvasive technique can reduce symptoms like hallucinations. Only 3 participants are enrolled, and the study is currently on hold.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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NYU Langone Health
New York, New York, 10016, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MRI-guided low-intensity focused ultrasound (LIFU) device
What this could lead to
If it works, this could point toward a new way to reduce hallucinations and other symptoms in people with schizophrenia that hasn't responded to standard treatments.
What could go wrong
This is a very early pilot study with only 3 participants, so results may not apply to others. The study is currently suspended, and the approach is still experimental with unknown effectiveness.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.