Medical University Of South Carolina

This study is testing a new program called ENHANCE-TTS that trains and supports pharmacists to provide tobacco treatment. It aims to help people living with HIV quit smoking, as this group has high smoking rates. The research will measure how well pharmacists adopt the program an…

This study is testing if a text message-based screening and referral program helps pregnant and postpartum women attend and stay in treatment for mental health or substance use issues better than the standard in-person screening method. Over 10,000 participants who are pregnant a…

This study is testing a faster version of a non-invasive brain stimulation treatment called iTBS to help people with depression and anxiety. Researchers are working with 70 participants to figure out the best dose of this treatment to reduce symptoms. They are also looking at how…

This study is testing a family-based program called FIT Families, designed specifically for African American teens with obesity and their caregivers. It compares this program to a standard support group to see which is better at helping families lose weight, become more active, a…

This study is testing a therapy that treats PTSD and substance use problems together in teenagers, instead of separately as is usually done. It compares a new family-based therapy to standard treatment to see which works better at reducing substance use and PTSD symptoms over a y…

This study is testing a non-invasive brain stimulation technique to see if it can help older adults with alcohol use disorder and mild memory problems. Researchers want to see if stimulating specific brain areas can reduce heavy drinking and improve thinking skills at the same ti…

This study is testing a new, highly targeted radiation technique for men with early-stage prostate cancer. The goal is to deliver a strong dose of radiation to the cancer while carefully avoiding nearby healthy areas like the urethra, rectum, and blood vessels. Researchers want t…

This study aimed to test a device called the Reflect Tether for children and teens with worsening scoliosis who are still growing. The device is attached to the curved spine to guide its growth into a straighter position, avoiding the need for spinal fusion surgery. The trial was…

This small pilot study is testing whether a new, non-invasive brain stimulation technique called low-intensity focused ultrasound (LIFUP) is safe and helpful for people with severe depression that hasn't improved with standard medications. The treatment aims to target a specific …

This study is comparing a new, automated laser treatment (DSLT) to the current standard laser treatment (SLT) for open-angle glaucoma. The goal is to see if the new, simpler method is as good at lowering eye pressure over 12 months. About 51 adults with glaucoma will be randomly …

This study is testing a 5-week behavioral therapy program designed for women who have experienced a sexual assault in the past year and are struggling with alcohol use. The goal is to see if this combined approach can help reduce symptoms of post-traumatic stress and control prob…

This study is testing a safe, noninvasive brain stimulation technique called focused ultrasound. Researchers aim to see if targeting a key memory area in the brain can improve memory function. The study will enroll 25 older adults, some with early memory concerns and some who are…

This study is testing a much shorter, 5-day radiation schedule given before surgery for soft tissue sarcoma in the arms or legs. The goal is to see if this approach is practical for patients and doctors, and if it works as well as the standard 5-6 week schedule. Researchers will …

This study is testing a new, quiet computer reminder for doctors. The reminder pops up in a patient's chart to suggest prescribing quit-smoking medication and referring patients for lung cancer screening. Researchers are comparing two groups of doctors to see if this tool changes…

This study is testing whether a daily cream containing rapamycin can help restore skin color in people with vitiligo. Participants will apply one of two strengths of the cream to a patch of skin on one side of their body and a placebo cream to a matching patch on the other side f…

This study is testing whether online medical visits can help people in rural areas quit smoking and get screened for COPD, a serious lung disease often caused by smoking. 144 adult smokers will be randomly assigned to either receive the online visit or not. The online visit asks …

This study is testing whether combining art therapy with standard physical therapy helps children feel better and recover physical abilities faster after a stem cell transplant. Eighteen children aged 5-18 will be randomly assigned to receive either the combined therapy or physic…

This study is testing whether having a certified therapy dog present during dental procedures can help reduce anxiety and improve behavior in children aged 3-7 who need an injection. Researchers will compare children who have a therapy dog with them to those who do not, measuring…

This study is testing a non-invasive brain stimulation treatment to see if it can safely improve thinking and memory problems in people who have had a stroke. Researchers are using a device called rTMS, which is already approved for depression, to see if it can help with stroke-r…

This study aims to see if stopping routine overnight neurological checks for stable stroke patients can help prevent delirium. The researchers believe that allowing patients to sleep through the night without interruptions might reduce confusion and improve recovery. They will co…

This study aimed to test whether a personalized form of gentle electrical brain stimulation could improve working memory in healthy older adults. Researchers planned to compare customized settings for the stimulation against standard settings and a placebo. The trial was withdraw…

This study is testing whether a skin patch containing a high concentration of capsaicin, the compound that makes chili peppers hot, can safely reduce chronic nerve pain in the lower back and legs. Up to 50 adults with this type of pain for over three months will apply up to four …

This study is testing whether daily bright light therapy can help reduce depression symptoms in older adults hospitalized for depression. Researchers will compare active light treatment to inactive placebo treatment in 20 patients aged 60 and older. The goal is to see if this non…

This study is testing whether a simple at-home ear stimulation device can help improve multiple symptoms for people with hypermobile Ehlers-Danlos syndrome (hEDS). Thirty participants will use the device for four weeks while researchers track changes in pain, fatigue, sleep, anxi…

This study aimed to test a new method for customizing the dose of a non-invasive brain stimulation technique called tDCS. Researchers wanted to see if a personalized dose could make the stimulation's effects on hand movement more consistent and stronger. The study was designed fo…

This research study aims to understand how the brain can change old, well-practiced movement patterns, like a bad golf swing. Researchers are testing a gentle, non-invasive brain stimulation technique on healthy adults while they perform computer tasks. The goal is to see if this…

This research study aimed to test a new wearable ultrasound device designed to gently stimulate a deep part of the brain involved in alertness. The goal was to see if this stimulation could improve reaction time and cognitive performance in healthy volunteers. The study was withd…

This study aims to understand if past lead exposure stored in bones makes mental illness more severe or affects how well brain stimulation treatments work. Researchers will measure bone-lead levels and track symptoms in 500 patients already enrolled in other mental health treatme…

This study aimed to see if a safe, non-invasive magnetic device could temporarily change brain activity to help healthy people make more rational decisions. It was not a treatment study, but was meant to gather basic knowledge for future research. The study was withdrawn before a…

This study is testing a new type of CT scanner to see if it can take clearer pictures during PET-CT scans for head and neck cancer. Twenty adult patients getting a standard PET-CT scan will also get a scan with the new machine. Researchers will compare the image quality from both…