Knee artery blocking procedure could cut pain and opioid use
NCT ID NCT05349682
First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This study tests whether blocking certain arteries in the knee (geniculate artery embolization) can reduce pain and the need for opioid painkillers in people with knee osteoarthritis. Twelve participants will receive the procedure and be followed for a year with MRI scans and pain questionnaires. The goal is to see if MRI can track the treatment's effects and if the procedure improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- geniculate artery embolization (a procedure that blocks certain blood vessels in the knee)
- What this could lead to
- If it works, this could offer a new, less invasive way to ease knee osteoarthritis pain and reduce the need for painkillers like opioids.
- What could go wrong
- This is a very small, early study with only 12 people and no comparison group. The procedure carries risks like any invasive treatment, and results may not apply to everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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