Medical University Of South Carolina

This study aims to adapt and test a shorter therapy for teens with PTSD. Researchers will first adjust a proven adult therapy called Written Exposure Therapy (WET) for people aged 12-18. Then, they will compare this adapted 5-7 session therapy to the current standard 12-16 sessio…

This study compares two laser procedures for glaucoma, a condition that damages the optic nerve and can lead to vision loss. Researchers want to see if a newer, non-contact laser method is as good as or better than the current standard at lowering eye pressure over a year. About …

This study compares three FDA-approved biologic medications (dupilumab, omalizumab, and mepolizumab) to determine which works best for chronic sinusitis with nasal polyps. Researchers will follow 504 adults with moderate-to-severe nasal polyps who choose biologic therapy to see w…

This small pilot study is testing whether mailing buprenorphine medication directly to patients' homes helps people with opioid addiction stay in treatment after leaving the hospital. The research aims to overcome common barriers like transportation problems and pharmacy access. …

This early-stage study is testing whether a gentle, non-invasive ultrasound aimed at a specific brain area is safe and might help improve social difficulties in people with autism. It will involve 20 teens and young adults (ages 13-25) with autism. Researchers will use brain scan…

This early study is testing whether a topical foam containing the antibiotic minocycline can safely and effectively treat a skin condition called Confluent and Reticulated Papillomatosis (CARP). Participants aged 9 and older will apply the foam to one side of their body and a bas…

This study is testing if a special dye called Indocyanine Green (ICG) can help surgeons see head and neck cancer tissue more clearly during surgery. The goal is to help remove all the cancer and lower the chance it comes back. About 30 adult patients will receive the dye before t…

This study is testing a new way to deliver a proven child abuse prevention program called SafeCare. Researchers want to see if combining in-person and virtual home visits can help the program reach more families in need, especially in rural or underserved areas. The pilot will in…

This study is testing whether taking a progesterone supplement early in pregnancy can prevent preeclampsia, a serious high blood pressure condition. It will involve 642 low-risk pregnant people who will either receive the progesterone treatment or standard prenatal care. Research…

This study is testing a special online therapy program called LiveWell, designed to help people living with advanced lung cancer. It aims to reduce distress, anxiety, and depression while improving overall quality of life. The program will be compared to usual care to see if it i…

This study is testing whether a non-invasive brain stimulation technique can help reduce chronic pain in the scrotum. It will involve 50 men who have experienced this pain for at least six months. Researchers will use a magnetic device to stimulate the brain over three days and t…

This study is testing whether hot saunas, cold baths, or a combination of both can improve sleep quality and help the brain's nightly cleaning process in military cadets. Researchers will enroll 45 cadets and track their sleep and mood using smart rings and questionnaires over se…

This small pilot study is testing whether adding brief daily mindfulness practice to an existing brain stimulation treatment helps people with depression. Twenty participants receiving standard brain stimulation therapy will use a mindfulness app during their treatment days. Rese…

This study is testing a mental health support program for family members of people who have survived intensive care. The program uses a telehealth platform to help families manage anxiety, depression, and stress. Researchers want to see if this approach is practical and helpful f…

This study tests whether a digital mental health program helps people recovering from intensive care. 150 patients will either use a special app with coaching and support or receive standard follow-up care. Researchers will compare anxiety, depression, and PTSD symptoms after six…

This research aims to understand how men and women with cannabis use disorder respond differently to THC, the main active ingredient in cannabis. Researchers will give 40 participants either THC or a placebo pill and use brain scans to measure how their brains process rewards. Th…

This study aims to understand how a new technology called focused ultrasound affects the brain in healthy people. Researchers will use sound waves to gently stimulate a specific brain area and measure changes in brain signals and chemicals. The goal is to learn how this tool work…

This study aims to understand how memory works in the aging brain by scanning healthy older adults while they perform memory tasks. Researchers will use special brain imaging equipment to see which brain areas are active during memory activities. The goal is to learn how the brai…