Medical University Of South Carolina

This study looks at whether people with HPV-related throat cancer can safely skip radiation after surgery if a blood test two weeks later shows no signs of cancer. About 36 patients will have robotic surgery and then be monitored with regular checkups and blood tests. The goal is…

This early-stage study tests a probiotic capsule containing five bacterial strains to treat moderate to severe acne in 34 adults aged 18-45. The approach aims to improve gut health, reduce inflammation, and explore links between blood sugar spikes and acne flare-ups. Participants…

This study tests whether a supplement called oleoylethanolamide (OEA) can reduce inflammation, improve thinking, and lower alcohol use in young adults aged 18–25 with alcohol use disorder. Participants will take OEA or a placebo daily for 6 weeks and provide blood, saliva, and ur…

This study tests whether a topical foam containing the antibiotic minocycline can safely and effectively treat confluent and reticulated papillomatosis (CARP), a skin condition that causes brown, scaly patches. About 35 people aged 9 and older will apply the foam to one side of t…

This study will compare three FDA-approved biologic drugs (dupilumab, omalizumab, and mepolizumab) in 504 adults with chronic sinusitis and nasal polyps. The goal is to see which drug works best for different patients and whether simple tests can predict who will improve the most…

This study tests whether taking progesterone as a vaginal pill early in pregnancy can prevent preeclampsia, a serious condition involving high blood pressure. Researchers will give 642 low-risk pregnant women either progesterone or standard care. The goal is to see if this simple…

This study tests a new approach to delivering the SafeCare program, which helps parents prevent child maltreatment. Researchers will work with 12 home visiting providers and 40 caregivers to see if a mix of in-person and virtual sessions can reach more families and improve parent…

This study tests whether a gentle nerve stimulation device (taVNS) used at home can improve walking, balance, and other symptoms in 16 adults with Parkinson's disease. Participants will self-administer 1-hour daily sessions for 8 weeks and complete brain scans, assessments, and q…

This small pilot study will test whether adding brief guided mindfulness exercises (using a smartphone app) to standard accelerated brain stimulation therapy can help people with major depression. Twenty adults already receiving the brain stimulation at the Medical University of …

This early-stage study tests whether a non-invasive ultrasound device can safely stimulate a deep brain region in 20 people with autism aged 13-25. Researchers will check for side effects and measure changes in social skills, emotion recognition, and brain activity. The goal is t…

This study tests a program called LiveWell, which teaches emotional coping skills to people with metastatic lung cancer who are feeling distressed. About 80 participants will either receive the LiveWell training or continue with their usual care. The goal is to see if LiveWell ca…

This study tests whether taking steroids after sleep surgery helps adults with obstructive sleep apnea feel less pain, eat normally sooner, and use fewer painkillers. About 120 adults will receive either steroids or a placebo for a short time after their operation. The goal is to…

This study tests a group therapy program called LiveWell mBC for women with metastatic breast cancer who feel distressed. The program uses adapted Dialectical Behavioral Therapy (DBT) skills to help manage emotions and uncertainty. Researchers will see if the program is practical…

This early study tests whether transcranial magnetic stimulation (TMS) can ease chronic scrotal pain in men. Fifty men with pain lasting at least 6 months will receive TMS and report their pain daily via text messages. The goal is to see if this non-invasive brain treatment is fe…

This study will use brain scans (EEG and fMRI) to watch how healthy older adults' brains maintain memories. Researchers want to find patterns that show when the brain is working well versus when it might be struggling. The goal is to better understand normal aging and find early …

This study uses focused ultrasound on the brain's motor area to see how it changes electrical signals and brain chemicals. It involves 25 healthy adults aged 18-55. The goal is to understand how ultrasound affects the brain, not to treat any disease.

This pilot study looks at how cold-water immersion, sauna use, or both together affect sleep quality and brain waste removal in 45 military cadets. Participants will wear a smart ring and a brain monitor to track sleep and body changes. The goal is to see if these temperature the…

This study looks at how teenagers who have experienced trauma react to stress and strong emotions. Researchers will measure brain activity, heart rate, and sweat responses while teens imagine a stressful event. The goal is to learn what predicts who will benefit from exposure-bas…