Can brain and body clues predict PTSD treatment success in teens?

NCT ID NCT07537764

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examines how 180 adolescents aged 14-18 with trauma-related symptoms react to stress and strong emotions. Researchers will measure brain activity, heart rate, and anxiety while teens repeatedly imagine details of their own traumatic event. The goal is to understand which biological and behavioral patterns might predict who responds best to exposure-based therapies for PTSD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Repeated imaginal exposure (script-driven imagery task)

What this could lead to

If successful, this could help identify which teens with PTSD are most likely to benefit from exposure-based therapies, leading to more personalized treatment.

What could go wrong

This is a very early, small study focused on understanding mechanisms, not testing a treatment. Results may not directly improve care or apply to all teens with PTSD.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact