Progesterone pill may stop dangerous pregnancy condition
NCT ID NCT07448597
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking progesterone early in pregnancy can prevent preeclampsia, a condition that causes high blood pressure and organ damage. Over 600 low-risk pregnant women will either receive nightly vaginal progesterone or standard care. Researchers will track who develops preeclampsia and other complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- vaginal progesterone
- What this could lead to
- If it works, this could offer a simple, low-cost way to prevent preeclampsia, a dangerous pregnancy complication.
- What could go wrong
- This is a phase 4 trial, but results are not yet available. The benefit may be small or absent, and progesterone can cause side effects like drowsiness or nausea.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HYPERTENSIVE DISORDER OF PREGNANCY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could cutting salt after childbirth tame dangerous blood pressure?
- Could a placental protein unlock the mystery of preeclampsia?
- Tiny particles in the blood may warn of dangerous pregnancy high blood pressure
- Vitamin d may cut risk of repeat preeclampsia in High-Risk pregnancies
- Depression drug may mend blood vessels damaged by preeclampsia
- Postpartum blood pressure control may stop preeclampsia from leading to lifelong hypertension