Progesterone pill may stop dangerous pregnancy condition
NCT ID NCT07448597
First seen Mar 17, 2026 · Last updated Jun 19, 2026 · Updated 22 times
Summary
This study tests whether taking progesterone early in pregnancy can prevent preeclampsia, a condition that causes high blood pressure and organ damage. Over 600 low-risk pregnant women will either receive nightly vaginal progesterone or standard care. Researchers will track who develops preeclampsia and other complications.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vaginal progesterone
What this could lead to
If it works, this could offer a simple, low-cost way to prevent preeclampsia, a dangerous pregnancy complication.
What could go wrong
This is a phase 4 trial, but results are not yet available. The benefit may be small or absent, and progesterone can cause side effects like drowsiness or nausea.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.