New radiation method aims to cut side effects in prostate cancer treatment

NCT ID NCT05668351

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new way to deliver high-dose radiation (SABR) for low- and intermediate-risk prostate cancer. The technique, called SUPR-SABR, is designed to avoid the urethra, rectum, and pudendal artery to reduce urinary and bowel side effects. About 42 men will receive five radiation sessions over 1-2 weeks, and researchers will track their quality of life and side effects for two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic ablative body radiotherapy (SABR) with urethra, pudendal artery, and rectum sparing

What this could lead to

If successful, this approach could reduce urinary and bowel side effects from radiation therapy for prostate cancer, making treatment more tolerable.

What could go wrong

This is a small, early-phase trial with only 42 participants and no comparison group. It is not yet known if the new technique controls cancer as well as standard SABR.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of South Carolina Hollings Cancer Center

    Charleston, South Carolina, 29425, United States