Could a common supplement help teens with alcohol problems?

NCT ID NCT05870111

Ongoing Disease control Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether citicoline, an over-the-counter supplement, can help young people ages 16 to 22 with alcohol use disorder. Over 4 weeks, participants receive either citicoline or a placebo. Researchers measure changes in immune markers, brain chemistry, and thinking skills to see if the supplement reduces harm from alcohol.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: citicoline (a dietary supplement)
What this could lead to: If it works, this could point toward a safe, over-the-counter supplement to help young people reduce alcohol-related brain and immune system harm.
What could go wrong: This is a small, early-stage trial with only 56 participants. The supplement may not show meaningful benefits over placebo, and results may not apply to all youth with alcohol use disorder.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER

Contacts and locations

Locations

Medical University of South Carolina

Charleston, South Carolina, 29425, United States

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