Could a common supplement help teens with alcohol problems?
NCT ID NCT05870111
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether citicoline, an over-the-counter supplement, can help young people ages 16 to 22 with alcohol use disorder. Over 4 weeks, participants receive either citicoline or a placebo. Researchers measure changes in immune markers, brain chemistry, and thinking skills to see if the supplement reduces harm from alcohol.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
citicoline (a dietary supplement)
What this could lead to
If it works, this could point toward a safe, over-the-counter supplement to help young people reduce alcohol-related brain and immune system harm.
What could go wrong
This is a small, early-stage trial with only 56 participants. The supplement may not show meaningful benefits over placebo, and results may not apply to all youth with alcohol use disorder.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States