Karolinska Institutet

This was a small, early-stage study to check if a new experimental vaccine for Crimean-Congo hemorrhagic fever is safe and can trigger an immune response. Fifteen healthy adults received three doses of the vaccine at different strengths. The main goal was to monitor for side effe…

This study tested whether an electronic alert system could help primary care doctors better identify and manage patients with chronic kidney disease (CKD). The system automatically flagged patients at risk and provided doctors with guideline-based advice. Researchers compared out…

This pilot study tested if a 'double sequential defibrillation' strategy—giving two rapid shocks as soon as possible—is feasible and safe for treating out-of-hospital cardiac arrest. It involved 40 patients and compared this approach to the standard single-shock method. The goal …

This study tested a personalized support program for people leaving the hospital after a stroke or mini-stroke (TIA). The program helped patients and their healthcare teams plan the transition home, focusing on understanding medications and managing health. Researchers compared 2…

This study tested if small abdominal hernias could be safely and effectively repaired in a regular clinic room using only local numbing medicine, instead of a full operating room. It involved 37 adults with small hernias to see if patients tolerated the procedure well and were sa…

This study tested a new method for diagnosing birch pollen allergies. Researchers sprayed a dissolved allergy tablet into the noses of 89 people to see if it could safely and effectively trigger and measure allergic reactions. The goal was to find a reliable replacement for an ol…

This study tested an online group program designed to help people with multiple sclerosis (MS) prevent falls. 240 participants who had experienced at least one fall in the past year were assigned to either take the 8-session online course or receive a standard brochure. Researche…

This study tested a new online program designed to help people with multiple sclerosis (MS) prevent falls. The program taught self-management strategies during weekly group sessions. Researchers wanted to see if the program was practical and acceptable, and if it helped participa…

This study tested whether sending a dental professional to clean the teeth of older adults at home every three months could prevent painful root cavities. It involved 194 home-living seniors who needed help with daily care. The goal was to see if this regular cleaning, combined w…

This study tested whether an online therapy program, specially adapted for Arabic-speaking refugee and migrant youth, could help reduce symptoms of anxiety, depression, and trauma. The program used internet-based cognitive behavioral therapy (iCBT) over 6-10 weeks. Researchers co…

This study tested whether a Swedish computer game called Grapholearn could help children with developmental language disorder improve their reading skills. Researchers compared 67 children playing the reading game to children playing a math game or attending regular school classe…

This study tested whether an internet-based cognitive behavior therapy (CBT) program could reduce symptoms of stress-related disorders like adjustment disorder and exhaustion disorder (burnout). It involved 300 participants and compared the online CBT program to a standard, struc…

This study tested a new, simpler method to help people regain their sense of smell after a viral infection like COVID-19. Researchers compared standard smell training, which requires active sniffing, to a new method using scented nose plugs worn passively. The goal was to see if …

This study tested whether spinal manipulation therapy combined with stretching exercises works better than stretching alone for people with long-term neck pain. Researchers measured how the treatment affected the body's stress response and pain sensitivity in 131 participants ove…

This study tested if a new, easy-to-access treatment could help children and teenagers with chronic stomach pain linked to gut-brain disorders. Researchers gave 32 Swedish kids audio files with hypnotherapy exercises to listen to at home for 12 weeks. The goal was to see if this …

This study tested if a simpler, nurse-led support program could be as helpful as a more intensive therapist-guided therapy for people with stress. It involved 172 primary care patients with mild-to-moderate stress symptoms. Researchers compared a collaborative care model led by a…

This study tested a breathing exercise program for adults struggling with Long COVID symptoms like fatigue and shortness of breath. Researchers wanted to see if training the breathing muscles twice a day for eight weeks, combined with physical exercise, could improve breathing st…

This study aimed to understand what children with hearing loss and their parents know about the cause of the condition. Researchers surveyed 156 children and their caregivers using questionnaires to see if they knew the reason for the hearing loss and how important that knowledge…

This project aimed to create and test a better system for helping stroke patients move from the hospital back to their homes. Researchers worked directly with stroke survivors, their families, and healthcare staff to design a more personalized and coordinated transition plan. The…

This study looked at whether the depth of sedation (how deeply asleep a patient is) during a common gallstone removal procedure affects whether stones are left behind and require a second procedure. Researchers analyzed data from over 120,000 procedures performed in Sweden. The g…

This study used health records from over 250,000 Swedish men to understand if PSA blood tests for prostate cancer help men aged 75 to 79 live longer. Researchers compared men who had the test to those who didn't, tracking them for up to 16 years. The goal is to see if screening g…

This study aimed to understand if having type 2 diabetes changes a person's risk of getting malaria and other parasitic worm infections. Researchers in Cameroon followed 406 adults, some with diabetes and some without, for one year. They tested blood and stool samples regularly t…