Karolinska Institutet

This large Swedish study aims to find the best approach for patients with two groin hernias where only one is causing symptoms. It will compare repairing both hernias at once versus only fixing the painful side, leaving the 'silent' one alone. The goal is to see which strategy le…

This study is testing a 9-month support program to help new mothers improve their heart health after a first pregnancy complicated by preeclampsia. The program uses a special smartphone app for tracking blood pressure and weight, along with online coaching and group meetings. Res…

This study is testing whether a 10-week educational program focused on health behaviors can help women with a condition called functional hypothalamic amenorrhea (FHA) get their menstrual periods back and improve their hormone levels. Researchers will compare the program to stand…

This study is testing whether adding a digital health app to standard weight-loss medication leads to better results for teenagers with obesity. Researchers will compare teens using both the app and medication to those using medication alone over six months. The app allows for da…

This study is for people with breast cancer that has spread to lymph nodes in the armpit, which is visible on an ultrasound before surgery. It will test if a less extensive surgery, which removes only the first few key lymph nodes, is just as effective for survival as the standar…

This study is testing a coordinated family support program that combines school-based health education with targeted parental coaching to help prevent and manage childhood obesity. Researchers will work with 126 families of children aged 6-12 who have overweight or obesity, compa…

This study is testing a 6-month lifestyle program designed to help prevent memory decline in adults aged 60 and older who are at higher risk for dementia. It compares a supervised, structured version of the program to a self-guided version. The program includes guidance on nutrit…

This study is testing a shorter version of a proven parenting therapy, enhanced with instructional videos and virtual reality (VR) practice sessions. It aims to help parents of children aged 2-7 who are struggling with disruptive behaviors like defiance and aggression. The resear…

This study is testing whether weekly yoga sessions, offered either online or in-person, can help adults with chronic migraines or cluster headaches. Researchers aim to see if this gentle exercise improves sleep, reduces stress, and lessens headache frequency and intensity. The go…

This study aims to understand how muscle strength and fitness affect people born with single-chamber hearts who've had Fontan surgery. Researchers will measure muscle mass, strength, exercise capacity, and quality of life in 40 patients and compare them to healthy volunteers. The…

This study aims to understand screen use habits in families with young children (0-5 years old) and how child health nurses address this topic. Researchers will survey about 300 parents and interview some parents and nurses to learn about daily screen time, family rules, and expe…

This research aims to better understand and predict mood episodes in bipolar disorder. Researchers will track 600 participants' sleep, activity, and decision-making using smartwatches and computer tasks. The goal is to find patterns that can help distinguish bipolar disorder from…

This study aims to better understand how heart and blood vessel problems affect people with severe sepsis. Researchers will observe 400 adults hospitalized with sepsis who need medication to support their blood pressure. They will perform heart ultrasounds, blood tests, and check…

This study aims to test how well a special device can measure the energy used by critically ill babies and small children (under 10kg) in the intensive care unit. Researchers will observe 80 infants to see if the device works reliably and to understand their energy needs during i…

This research aims to understand how people with intellectual disability (ID) process emotions compared to people with autism and typically developing individuals. It will also test a 24-week therapy program adapted from Dialectical Behavior Therapy to help people with ID better …

This study aims to understand patient experiences with two different talk therapies for anxiety disorders. Researchers will interview 30 adults with generalized anxiety, social anxiety, or PTSD who have already completed one of the therapies. The goal is to learn what patients fo…

This study aims to find patterns in psychiatric care records that might signal increased risk of criminal behavior. Researchers will compare medical records of 500 people who committed crimes with those who didn't, looking at the three months before the offense. The goal is to he…

This study aims to understand how well a Swedish child health program works to identify family violence. Researchers will look at the medical records of about 90,000 children to see if nurses asked their parents about violence at home. They will also interview nurses to learn abo…