Jonsson Comprehensive Cancer Center

This early-stage study is testing the safety and best dose of a new type of CAR-T cell therapy for patients with B-cell lymphomas or chronic lymphocytic leukemia that has come back or hasn't responded to other treatments. Doctors take a patient's own immune cells, modify them in …

This study is testing a shorter, more targeted form of radiation therapy for men whose prostate cancer was surgically removed but who are at high risk of it coming back. The goal is to see if this precise, 5-session treatment can effectively control the cancer while causing fewer…

This study is testing a two-part treatment for advanced cancer. Doctors take a patient's own white blood cells, genetically modify them to recognize a specific cancer protein (NY-ESO-1), and infuse them back. This is combined with a vaccine made from the same protein to boost the…

This trial is testing a combination of three drugs (niraparib, temozolomide, and atezolizumab) to see if they work better together to control advanced cancers, especially a type called extensive-stage small cell lung cancer. The study first finds a safe dose, then compares the th…

This study is testing a combination of three drugs for people with advanced lung cancer that has a specific genetic change (EGFR mutation) and has stopped responding to the usual treatment. The goal is to see if adding two antibody drugs (trastuzumab and necitumumab) to the stand…

This early-stage trial is testing whether adding the immunotherapy drug pembrolizumab to standard chemotherapy works better for treating advanced small cell or neuroendocrine cancers of the bladder, urethra, or prostate. The study will enroll about 15 participants with cancer tha…

This study is testing a focused, high-dose radiation treatment called SBRT for men with high-risk prostate cancer that hasn't spread. The goal is to see if this shorter treatment schedule (5 sessions over 2 weeks) can effectively control the cancer while minimizing side effects a…

This early-stage study is testing the safety of combining two immunotherapy drugs, nivolumab and BO-112, given before surgery for patients with operable soft tissue sarcoma. The goal is to see if stimulating the immune system to attack the tumor before it is removed can improve o…

This study is testing whether a plant-based nutrition drink can help people with head and neck cancer avoid needing a feeding tube during their chemoradiation treatment. Researchers want to see if this easy-to-digest, allergen-free drink provides enough calories and protein to ma…

This is a small, early-stage study to see if a personalized vaccine is safe for patients with a rare and aggressive brain tumor called H3 G34-mutant glioma. The vaccine is made from the patient's own immune cells and is designed to teach the body to attack the tumor. Researchers …

This study is testing whether a combination of two drugs, talazoparib and temozolomide, can help control extensive-stage small cell lung cancer that has come back or stopped responding to initial chemotherapy. It will involve about 35 participants. The goal is to see if using the…

This study is testing a new way to deliver radiation therapy along with standard chemotherapy for people with stage II or III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if a more targeted, higher-dose radiation schedule can kill more cancer c…

This study is testing a two-part treatment for prostate cancer that has returned and spread to a few other areas of the body. Patients receive hormone-blocking drugs for six months, combined with highly targeted radiation to the specific tumors. The goal is to see if this combine…

This study is comparing two different imaging methods used to guide radiation treatment for prostate cancer. It aims to see if using MRI scans to guide the radiation causes fewer side effects, like urinary or bowel problems, compared to the standard CT scan method. About 180 men …

This study is testing whether combining a targeted form of internal radiation (brachytherapy) with immunotherapy drugs can help control advanced gynecologic cancers that have stopped responding to standard platinum-based chemotherapy. It aims to see if this two-pronged approach i…

This study is testing a new, experimental type of MRI scan designed to see brain tumors (gliomas) in more detail. The goal is to see if this scan can provide better information about the tumor's biology and how it might respond to treatment. The study involves people with brain t…

This study compares two molecular tests used to evaluate thyroid nodules that have unclear biopsy results. The goal is to determine which test is better at identifying which nodules are truly cancerous and which are benign, helping patients avoid surgery they don't need. Research…

This study is testing a new way to find prostate cancer in men whose previous biopsy results were unclear or negative. Researchers are using a special radioactive tracer that sticks to prostate cancer cells, which shows up on a PET/CT scan. This scan then guides the doctor's biop…

This study is testing whether a specialized imaging scan called MIBI SPECT/CT can help doctors better identify the type of kidney tumor a patient has. The goal is to see if this scan provides clearer information that helps patients and doctors choose the most appropriate treatmen…

This study is testing a practical program to get more people screened for colorectal cancer, which is a leading cause of cancer deaths. It focuses on helping low-income and ethnic minority patients, who often face barriers to screening. The program provides clinics with training,…

This study is testing whether the gentle mind-body exercise Tai Chi can help improve chronic insomnia in women who have survived breast cancer. Researchers are comparing Tai Chi to standard cognitive behavioral therapy (CBT) to see which is better at improving sleep quality, redu…

This study is testing if using Soylent, a liquid meal replacement, can help patients with head and neck cancer avoid needing a feeding tube during their intensive chemoradiation treatment. The goal is to see if better nutrition from Soylent can reduce malnutrition and the need fo…

This study is testing whether watching educational videos can help people who have survived a rare eye cancer called uveal melanoma. The goal is to see if changing how patients think about their illness can reduce feelings of anxiety and depression during survivorship. About 108 …

This early-stage study is testing a new imaging agent called 68Ga-FAPI-46 to see where it goes in the body of patients with many different types of cancer. The goal is to understand if this tracer can help doctors better see and understand tumors by highlighting specific cells ar…

This study is testing whether a genetic test can predict which prostate cancer patients are at high or low risk for serious urinary and bowel side effects from a specific type of radiation therapy. About 208 men with early-stage prostate cancer will take the test, and then discus…