New cocktail aims to outsmart Drug-Resistant lung cancer

NCT ID NCT04285671

First seen Mar 10, 2026 · Last updated May 06, 2026 · Updated 10 times

Summary

This study tests whether adding two antibody drugs (necitumumab and trastuzumab) to the standard pill osimertinib can shrink tumors in people with advanced EGFR-mutated lung cancer that has stopped responding to osimertinib alone. About 30 adults with stage IV non-small cell lung cancer will receive the combination to find the safest dose and measure how well it works. The goal is to control the cancer, not cure it, since ongoing treatment is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UCLA / Jonsson Comprehensive Cancer Center

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.