Better swab, better catch: study aims to sharpen anal cancer screening
NCT ID NCT02816879
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This study compares different ways to collect anal cell samples and different HPV tests to see which combination best predicts high-grade anal dysplasia, a pre-cancerous condition. Researchers are enrolling men who have sex with men, including those with and without HIV. The goal is to make screening more accurate so that those at highest risk can be identified and treated earlier.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to simpler, more accurate screening to catch pre-cancerous changes early in men at higher risk.
- What could go wrong
- This is an observational comparison of existing tests, not a treatment trial. Results may not change current screening guidelines.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Desert AIDS Project
Palm Springs, California, 92262, United States
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Los Angeles Gay and Lesbian Center
Los Angeles, California, 90028, United States
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UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095, United States
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