New drug combo shows promise for tough lung cancer
NCT ID NCT03672773
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a combination of two drugs, talazoparib and temozolomide, in 35 people with extensive-stage small cell lung cancer that came back after initial chemotherapy. Talazoparib blocks cancer cells from repairing their DNA, while temozolomide is a chemotherapy that kills cancer cells. The goal is to see if this combination works better than either drug alone in shrinking tumors and controlling the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CBCC Global Research, Inc. at Comprehensive Blood and Cancer Center
Bakersfield, California, 93309, United States
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Cancer Center of Kansas
Wichita, Kansas, 67214, United States
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Ft. Wayne Medical Oncology and Hematology, Inc.
Fort Wayne, Indiana, 46804, United States
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Orlando Health, Inc. d/b/a Orlando Health UF Health Center
Orlando, Florida, 32806, United States
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St. Joseph Heritage Healthcare
Fullerton, California, 92835, United States
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UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095, United States