SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

This study is testing a live attenuated dengue vaccine (Butantan-DV) in 477 people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) and in healthy volunteers. The goal is to see if the vaccine is safe and produces a strong immune response …

This study follows 200 adults with systemic lupus erythematosus (SLE) who are starting anifrolumab for the first time as part of their usual care. Researchers will track disease activity, skin symptoms, fatigue, and quality of life over time using standard medical assessments. Th…

This early-phase study tests a new treatment called BZE2204 for people with severe autoimmune diseases like lupus, myositis, and ITP that have not responded to standard therapies. The treatment uses a patient's own immune cells, which are modified in a lab to target and attack fa…

This study tests an experimental injection called DB-2304 in healthy volunteers and people with lupus (SLE or CLE). The main goal is to check safety and side effects, not to cure the disease. About 148 participants will be monitored closely. If safe, the drug may help control lup…

This early-stage study tests a single injection of stem cells from donated umbilical cords for people with active lupus. Ten adults will receive the cells alongside their usual care. Researchers will check if the treatment is safe and if it helps reduce disease activity and prote…

This early-stage trial tests a new treatment called FT819 for people with certain autoimmune diseases like lupus, vasculitis, myositis, and scleroderma. The treatment aims to target and control the immune cells that cause these diseases. The study will check if FT819 is safe and …

This study is building a large database of medical information and biological samples from 3,500 people with lupus. Researchers will use this resource to study the genetic and immune system factors that drive the disease. The goal is to better understand lupus and help develop mo…