New lupus kidney trial aims to ditch steroids without sacrificing control

NCT ID NCT04702256

First seen Dec 12, 2025 · Last updated Jun 04, 2026 · Updated 22 times

Summary

This study tests whether a new drug combination (obinutuzumab plus mycophenolate mofetil) can control lupus-related kidney inflammation without the need for oral steroids. About 196 people with active lupus nephritis will be randomly assigned to either the standard steroid-based regimen or the steroid-free approach. The goal is to see if the steroid-free option works just as well while avoiding the serious side effects of long-term steroid use.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Internal medicine, Cochin hospital, APHP

    RECRUITING

    Paris, 75014, France

    Contact

Conditions

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