Cord blood cells could tame lupus in first human test

NCT ID NCT06737380

Recruiting now Disease control Sponsor: LiveKidney.Bio Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial is testing whether a single injection of stem cells from donated umbilical cords is safe for people with active lupus. Ten adults will receive the cells alongside their usual care. Researchers will monitor side effects and check for signs that lupus activity and kidney function improve.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: umbilical cord derived mesenchymal stromal cells (UC-MSCs)
What this could lead to: If this early trial shows the cells are safe and reduce lupus activity, it could point toward a new treatment option for people with lupus.
What could go wrong: This is a very small, early-phase safety study with only 10 participants. It is not designed to prove the treatment works, and side effects or lack of benefit are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lupus erythematosus systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUPUS SLE SYSTEMIC LUPUS ERTHEMATOSUS SYSTEMIC LUPUS ERYTHEMATOSUS SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Contacts and locations

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Locations

Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States

Contact Email: •••••@•••••

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