LUPUS

This study is testing a new combination treatment for people with severe autoimmune diseases like lupus and scleroderma who haven't responded well to standard therapies. It involves giving specially modified immune cells (AD-PluReceptor-NK cells) along with a drug called tafasita…

This study is testing if baricitinib, a drug used for other immune conditions, is safe for people with Job syndrome who also have lupus-like disease or a severe skin rash (atopic dermatitis). It will enroll about 20 participants aged 12 and older. The main goal is to check for si…

This early-stage study is testing a new oral drug called ONTO1 for people with lupus, including a serious kidney complication called lupus nephritis. The main goal is to find the highest safe dose and see if it helps improve symptoms when taken alongside standard lupus medication…

This study is testing a personalized cell therapy called CART19 for adolescents and young adults with severe lupus that hasn't responded to standard treatments. Doctors will collect a patient's own immune cells, modify them to target lupus-causing B cells, and reinfuse them. The …

This early-stage study is testing whether adding a single injection of stem cells from umbilical cords to standard lupus treatment is safe and tolerable. It will involve 10 adults with active lupus to see if the therapy can reduce disease activity and improve kidney function. The…

This is an early safety study for a new drug called BMS-986326 for people with different types of lupus. The main goal is to see if the drug is safe and how the body processes it when given in increasing doses. Researchers will also check if the drug affects certain immune cells …

This study is comparing two online programs to see which works better for managing chronic pain. One is an 8-week cognitive behavioral therapy course, and the other is a single 2-hour skills class. Researchers at Stanford University are recruiting 1,650 adults with ongoing pain t…

This study is testing whether an online group therapy program can help reduce chronic pain and improve quality of life for people with lupus who also have fibromyalgia. Researchers want to see if this emotional awareness therapy is safe and effective when delivered through video …

This is a long-term research project gathering health information from 10,000 people in the U.S. to build a detailed picture of brain inflammation and related conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants, including both affected and healthy individual…

This study aims to better understand the different types and causes of fatigue, which is a common symptom in many conditions like cancer, lupus, and chronic fatigue syndrome. Researchers will enroll about 700 adults, both with and without fatigue, to complete questionnaires, phys…