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Lupus drug trial aims for remission without daily pills

NCT ID NCT07598396

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests a drug called mosunetuzumab in 30 people with lupus, a disease where the immune system attacks the body. The goal is to see if the drug can put lupus into remission so that participants can stop most lupus medications for at least 6 months. However, some people may still need low-dose steroids or other treatments long-term, so this is not a cure.

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Conditions

The condition(s) this trial relates to.

lupus erythematosus lupus nephritis systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUPUS LUPUS NEPHRITIS SYSTEMIC LUPUS ERYTHEMATOSUS

Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili)

    RECRUITING

    Brescia, Lombardy, 25123, Italy

  • Centro de Investigacion en Reumatologia y Especialdades Medicas SAS. CIREEM

    RECRUITING

    Bogotá, 110221, Colombia

  • Clinica de la Costa S.A.S

    RECRUITING

    Barranquilla, 080020, Colombia

  • Clinical Trials Network Helderberg

    RECRUITING

    Somerset West, Western Cape, 7130, South Africa

  • Clnica SER da Bahia

    RECRUITING

    Salvador, Estado de Bahia, 40150-150, Brazil

  • Complexo Hospitalar de Niteroi

    RECRUITING

    Niterói, Rio de Janeiro, 24030-103, Brazil

  • Emmed Research

    RECRUITING

    Pretoria, Gauteng, 0002, South Africa

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Rome, Lazio, 00168, Italy

  • Hospital Pablo Tobon Uribe

    RECRUITING

    Medellín, 050034, Colombia

  • Hospital das Clinicas de Ribeirao Preto

    RECRUITING

    Ribeiro Preto, São Paulo, 14048-900, Brazil

  • Hospital das Clnicas da Faculdade de Medicina da USP

    RECRUITING

    São Paulo, São Paulo, 05403-000, Brazil

  • IPC MT Instituto de Pesquisas Clinicas do Mato Grosso

    RECRUITING

    Cuiab, Mato Grosso, 78020-500, Brazil

  • L2IP ?Instituto de Pesquisas Clínicas Ltda.

    RECRUITING

    Brasília, Federal District, 70200-730, Brazil

  • LMK Servios Mdicos S/S Ltda

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90480-000, Brazil

  • University of Cape Town Kidney and Hypertension Research Unit

    RECRUITING

    Cape Town, Western Cape, 7925, South Africa

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