Lupus patients who failed multiple drugs under observation in new study
NCT ID NCT07175285
First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This study is observing 223 people with active lupus (including kidney inflammation) who haven't gotten better with steroids and at least two immunosuppressants. Researchers want to see how well today's standard treatments work for these tough cases. The goal is to measure how many patients reach remission or low disease activity after 6 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AA MRC
RECRUITINGGrand Blanc, Michigan, 48439-2451, United States
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ASST degli Spedali Civili di Brescia
RECRUITINGBrescia, 25123, Italy
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Arizona Arthritis & Rheumatology Associates (AARA), P.C. - Mesa
RECRUITINGMesa, Arizona, 85210, United States
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Arthritis & Rheumatism Associates
RECRUITINGRockville, Maryland, 20850, United States
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Arthritis Care of Texas - Corpus Christi
RECRUITINGCorpus Christi, Texas, 78415, United States
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Azienda Ospedaliera Ordine Mauriziano di Torino
RECRUITINGTorino, TO, 10128, Italy
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Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant'Anna
RECRUITINGFerrara, RE, 44124, Italy
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CHU Hopitaux de Bordeaux - Groupe Hospitalier Pellegrin
RECRUITINGBordeaux, 33076, France
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Carmel Medical Center
RECRUITINGHaifa, 34362, Israel
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Centre for Rheumatology, Immunology and Arthritis
RECRUITINGFort Lauderdale, Florida, 33309-1715, United States
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Centre hospitalier de l'Université Laval
RECRUITINGCalgary, Alberta, T2T 5C7, Canada
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Centro de Investigaciones Medicas Tucuman
RECRUITINGSan Miguel de Tucumán, Tucumán Province, T4000AXL, Argentina
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DJL Clinical Research, PLLC
RECRUITINGCharlotte, North Carolina, 28211, United States
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El Paso Medical Research Institute (MedResearch, Inc)
RECRUITINGEl Paso, Texas, 79902-4821, United States
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, 08036, Spain
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Hospital de Merida
RECRUITINGMérida, Badajoz, 6800, Spain
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Hospital of the University of Occupational and Environmental Health, Japan
RECRUITINGKitakyushu-Shi, 807-8556, Japan
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Hôpital Saint-Antoine
RECRUITINGParis, Île-de-France Region, 75012, France
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Hôpitaux Universitaires de Strasbourg - Hôpital de Hautepierre
RECRUITINGStrasbourg, 67098, France
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Instituto De Reumatologia - IR Medical Center - Hospital de Dia
RECRUITINGMendoza, M5500CPH, Argentina
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Instituto Médico CER
RECRUITINGQuilmes, Buenos Aires, B1878DVB, Argentina
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King's College Hospital NHS Foundation Trust
RECRUITINGLondon, SE5 9RS, United Kingdom
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Kings County Hospital Center - Brooklyn
RECRUITINGBrooklyn, New York, 11203, United States
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LIFE Clinical Trials
RECRUITINGMargate, Florida, 33063, United States
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Local Institution - 0001
NOT_YET_RECRUITINGLa Palma, California, 90623-1730, United States
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Local Institution - 0005
NOT_YET_RECRUITINGPorto Alegre, Rio Grande do Sul, 90035-903, Brazil
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Local Institution - 0007
NOT_YET_RECRUITINGPorto Alegre, Rio Grande do Sul, 90610-000, Brazil
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Local Institution - 0025
NOT_YET_RECRUITINGTel Aviv, 6423906, Israel
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Local Institution - 0034
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109-5000, United States
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Local Institution - 0037
NOT_YET_RECRUITINGDurham, North Carolina, 27710-1000, United States
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Local Institution - 0038
NOT_YET_RECRUITINGSherbrooke, Quebec, J1G 2E8, Canada
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Local Institution - 0041
NOT_YET_RECRUITINGKiel, Schleswig-Holstein, 24105, Germany
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Local Institution - 0042
NOT_YET_RECRUITINGSão Paulo, 05403-000, Brazil
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Local Institution - 0043
NOT_YET_RECRUITINGMainz, 55131, Germany
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Local Institution - 0046
NOT_YET_RECRUITINGSan Juan, PR, 00917-3104, Puerto Rico
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Local Institution - 0051
NOT_YET_RECRUITINGVan Vleck, Texas, 77482, United States
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Local Institution - 0052
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
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Local Institution - 0053
NOT_YET_RECRUITINGSendai, Miyagi, 980-8574, Japan
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Local Institution - 0054
NOT_YET_RECRUITINGLa Jolla, California, 92093, United States
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Local Institution - 0055
NOT_YET_RECRUITINGWakayama, 641-8510, Japan
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Local Institution - 0069
NOT_YET_RECRUITINGAtlanta, Georgia, 30322-1013, United States
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Local Institution - 0070
NOT_YET_RECRUITINGKalispell, Montana, 59901-3129, United States
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Local Institution - 0071
NOT_YET_RECRUITINGLos Angeles, California, 90095, United States
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Local Institution - 0072
NOT_YET_RECRUITINGLund, Skåne County, SE-221 85, Sweden
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Local Institution - 0073
NOT_YET_RECRUITINGSolna, Stockholm County, 171 64, Sweden
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Local Institution - 0074
NOT_YET_RECRUITINGÖrebro, 701 85, Sweden
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Meir Medical Center
RECRUITINGKfar Saba, M, 4428164, Israel
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Murfreesboro Medical Clinic
RECRUITINGMurfreesboro, Tennessee, 37128, United States
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Oklahoma Medical Research Foundation
RECRUITINGOklahoma City, Oklahoma, 73104-5005, United States
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One- Rheumatology
RECRUITINGPalm Beach Gardens, Florida, 33410, United States
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Organización Médica de Investigación (OMI)
RECRUITINGBuenos Aires, C1015ABO, Argentina
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Oxford University Hospitals NHS Trust - Churchill Hospital
RECRUITINGOxford, OXF, OX3 7LE, United Kingdom
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Rabin Medical Center - Hasharon Hospital
RECRUITINGPetah Tikva, 4941492, Israel
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Rambam Medical Center
RECRUITINGHaifa, 31096, Israel
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Rheumatology Center of San Diego
RECRUITINGSan Diego, California, 92128-2551, United States
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Royal National Hospital for Rheumatic Diseases-Bath
RECRUITINGBath, SOM, BA1 3NG, United Kingdom
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Sahni Rheumatology & Therapy
RECRUITINGWest Long Branch, New Jersey, 07764, United States
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Sheba Medical Center
RECRUITINGRamat Gan, TA, 5262000, Israel
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South Florida Rheumatology
RECRUITINGHollywood, Florida, 33021-6052, United States
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St. Joseph's Hospital
RECRUITINGLondon, Ontario, N6A 4V2, Canada
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The Ottawa Hospital - General Campus
RECRUITINGOttawa, Ontario, K1H 8L6, Canada
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The Royal Free London NHS Foundation Trust - The Royal Free Hospital
RECRUITINGLondon, NW3 2QG, United Kingdom
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The Royal Wolverhampton NHS Trust - New Cross Hospital
RECRUITINGWolverhampton, West Midlands, WV10 0QP, United Kingdom
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Toyama University
RECRUITINGToyama, Toyama, 930-0887, Japan
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Willow Rheumatology & Wellness
RECRUITINGWillowbrook, Illinois, 60527, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A simple blood test may reveal kidney damage in lupus — no biopsy needed?
- Can a Three-Drug combo quiet lupus kidney flares?
- Can a new antibody tame lupus flares?
- Can a single infusion tame tough lupus?
- Can a single infusion of reprogrammed immune cells quiet lupus kidney disease?
- Can a smartphone app bridge the lupus care gap for women of color?