Lupus patients who failed multiple drugs under observation in new study

NCT ID NCT07175285

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study is observing 223 people with active lupus (including kidney inflammation) who haven't gotten better with steroids and at least two immunosuppressants. Researchers want to see how well today's standard treatments work for these tough cases. The goal is to measure how many patients reach remission or low disease activity after 6 months.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AA MRC

    RECRUITING

    Grand Blanc, Michigan, 48439-2451, United States

  • ASST degli Spedali Civili di Brescia

    RECRUITING

    Brescia, 25123, Italy

  • Arizona Arthritis & Rheumatology Associates (AARA), P.C. - Mesa

    RECRUITING

    Mesa, Arizona, 85210, United States

  • Arthritis & Rheumatism Associates

    RECRUITING

    Rockville, Maryland, 20850, United States

  • Arthritis Care of Texas - Corpus Christi

    RECRUITING

    Corpus Christi, Texas, 78415, United States

  • Azienda Ospedaliera Ordine Mauriziano di Torino

    RECRUITING

    Torino, TO, 10128, Italy

  • Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant'Anna

    RECRUITING

    Ferrara, RE, 44124, Italy

  • CHU Hopitaux de Bordeaux - Groupe Hospitalier Pellegrin

    RECRUITING

    Bordeaux, 33076, France

  • Carmel Medical Center

    RECRUITING

    Haifa, 34362, Israel

  • Centre for Rheumatology, Immunology and Arthritis

    RECRUITING

    Fort Lauderdale, Florida, 33309-1715, United States

  • Centre hospitalier de l'Université Laval

    RECRUITING

    Calgary, Alberta, T2T 5C7, Canada

  • Centro de Investigaciones Medicas Tucuman

    RECRUITING

    San Miguel de Tucumán, Tucumán Province, T4000AXL, Argentina

  • DJL Clinical Research, PLLC

    RECRUITING

    Charlotte, North Carolina, 28211, United States

  • El Paso Medical Research Institute (MedResearch, Inc)

    RECRUITING

    El Paso, Texas, 79902-4821, United States

  • Hospital Clínic de Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital de Merida

    RECRUITING

    Mérida, Badajoz, 6800, Spain

  • Hospital of the University of Occupational and Environmental Health, Japan

    RECRUITING

    Kitakyushu-Shi, 807-8556, Japan

  • Hôpital Saint-Antoine

    RECRUITING

    Paris, Île-de-France Region, 75012, France

  • Hôpitaux Universitaires de Strasbourg - Hôpital de Hautepierre

    RECRUITING

    Strasbourg, 67098, France

  • Instituto De Reumatologia - IR Medical Center - Hospital de Dia

    RECRUITING

    Mendoza, M5500CPH, Argentina

  • Instituto Médico CER

    RECRUITING

    Quilmes, Buenos Aires, B1878DVB, Argentina

  • King's College Hospital NHS Foundation Trust

    RECRUITING

    London, SE5 9RS, United Kingdom

  • Kings County Hospital Center - Brooklyn

    RECRUITING

    Brooklyn, New York, 11203, United States

  • LIFE Clinical Trials

    RECRUITING

    Margate, Florida, 33063, United States

  • Local Institution - 0001

    NOT_YET_RECRUITING

    La Palma, California, 90623-1730, United States

  • Local Institution - 0005

    NOT_YET_RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

  • Local Institution - 0007

    NOT_YET_RECRUITING

    Porto Alegre, Rio Grande do Sul, 90610-000, Brazil

  • Local Institution - 0025

    NOT_YET_RECRUITING

    Tel Aviv, 6423906, Israel

  • Local Institution - 0034

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109-5000, United States

  • Local Institution - 0037

    NOT_YET_RECRUITING

    Durham, North Carolina, 27710-1000, United States

  • Local Institution - 0038

    NOT_YET_RECRUITING

    Sherbrooke, Quebec, J1G 2E8, Canada

  • Local Institution - 0041

    NOT_YET_RECRUITING

    Kiel, Schleswig-Holstein, 24105, Germany

  • Local Institution - 0042

    NOT_YET_RECRUITING

    São Paulo, 05403-000, Brazil

  • Local Institution - 0043

    NOT_YET_RECRUITING

    Mainz, 55131, Germany

  • Local Institution - 0046

    NOT_YET_RECRUITING

    San Juan, PR, 00917-3104, Puerto Rico

  • Local Institution - 0051

    NOT_YET_RECRUITING

    Van Vleck, Texas, 77482, United States

  • Local Institution - 0052

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

  • Local Institution - 0053

    NOT_YET_RECRUITING

    Sendai, Miyagi, 980-8574, Japan

  • Local Institution - 0054

    NOT_YET_RECRUITING

    La Jolla, California, 92093, United States

  • Local Institution - 0055

    NOT_YET_RECRUITING

    Wakayama, 641-8510, Japan

  • Local Institution - 0069

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322-1013, United States

  • Local Institution - 0070

    NOT_YET_RECRUITING

    Kalispell, Montana, 59901-3129, United States

  • Local Institution - 0071

    NOT_YET_RECRUITING

    Los Angeles, California, 90095, United States

  • Local Institution - 0072

    NOT_YET_RECRUITING

    Lund, Skåne County, SE-221 85, Sweden

  • Local Institution - 0073

    NOT_YET_RECRUITING

    Solna, Stockholm County, 171 64, Sweden

  • Local Institution - 0074

    NOT_YET_RECRUITING

    Örebro, 701 85, Sweden

  • Meir Medical Center

    RECRUITING

    Kfar Saba, M, 4428164, Israel

  • Murfreesboro Medical Clinic

    RECRUITING

    Murfreesboro, Tennessee, 37128, United States

  • Oklahoma Medical Research Foundation

    RECRUITING

    Oklahoma City, Oklahoma, 73104-5005, United States

  • One- Rheumatology

    RECRUITING

    Palm Beach Gardens, Florida, 33410, United States

  • Organización Médica de Investigación (OMI)

    RECRUITING

    Buenos Aires, C1015ABO, Argentina

  • Oxford University Hospitals NHS Trust - Churchill Hospital

    RECRUITING

    Oxford, OXF, OX3 7LE, United Kingdom

  • Rabin Medical Center - Hasharon Hospital

    RECRUITING

    Petah Tikva, 4941492, Israel

  • Rambam Medical Center

    RECRUITING

    Haifa, 31096, Israel

  • Rheumatology Center of San Diego

    RECRUITING

    San Diego, California, 92128-2551, United States

  • Royal National Hospital for Rheumatic Diseases-Bath

    RECRUITING

    Bath, SOM, BA1 3NG, United Kingdom

  • Sahni Rheumatology & Therapy

    RECRUITING

    West Long Branch, New Jersey, 07764, United States

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, TA, 5262000, Israel

  • South Florida Rheumatology

    RECRUITING

    Hollywood, Florida, 33021-6052, United States

  • St. Joseph's Hospital

    RECRUITING

    London, Ontario, N6A 4V2, Canada

  • The Ottawa Hospital - General Campus

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

  • The Royal Free London NHS Foundation Trust - The Royal Free Hospital

    RECRUITING

    London, NW3 2QG, United Kingdom

  • The Royal Wolverhampton NHS Trust - New Cross Hospital

    RECRUITING

    Wolverhampton, West Midlands, WV10 0QP, United Kingdom

  • Toyama University

    RECRUITING

    Toyama, Toyama, 930-0887, Japan

  • Willow Rheumatology & Wellness

    RECRUITING

    Willowbrook, Illinois, 60527, United States

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Other studies related to the condition(s) this trial covers.