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Could a dengue vaccine be safe for autoimmune patients? new trial aims to find out

NCT ID NCT07087912

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: University of Sao Paulo General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the Butantan-Dengue vaccine is safe and works well in people aged 12–59 with autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are stable on low or no immune-suppressing drugs. Participants receive one vaccine dose and are monitored for side effects and immune response for a year. Results will be compared to healthy volunteers to see if the vaccine triggers similar protection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy antiphospholipid syndrome Axial Spondyloarthritis Behcet disease granulomatosis with polyangiitis juvenile idiopathic arthritis microscopic polyangiitis myositis disease psoriatic arthritis rheumatoid arthritis spondyloarthropathy systemic lupus erythematosus systemic sclerosis Takayasu arteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTIPHOSPHOLIPID SYNDROME AXIAL SPONDYLOARTHRITIS BEHCET'S DISEASE GRANULOMATOSIS WITH POLYANGIITIS IDIOPATHIC INFLAMMATORY MYOPATHIES (IIMS) JUVENILE IDIOPATHIC ARTHRITIS (JIA) JUVENILE SYSTEMIC LUPUS ERYTHEMATOSUS MICROSCOPIC POLYANGIITIS PSORIATIC ARTHRITIS (PSA) RHEUMATOID ARTHRITIS (RA SJÖGREN'S DISEASE SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) SYSTEMIC SCLEROSIS (SSC) TAKAYASU ARTERITIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital das Clínicas da Faculdade de Medicina da USP

    RECRUITING

    São Paulo, São Paulo, 01246-903, Brazil

  • Rheumatology Division, Faculdade de Medicina da USP

    RECRUITING

    São Paulo, São Paulo, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••