PSORIATIC ARTHRITIS (PSA)

This study is testing a live attenuated dengue vaccine (Butantan-DV) in people aged 12–59 with autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are stable and on low or no immune-suppressing drugs. Researchers want to see if the vaccine triggers a good immun…

This study tests whether people with rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis who are doing well on a JAK inhibitor can safely lower their dose without losing disease control. About 200 participants will either follow a guided dose-reduction plan or c…

This early-stage study tests an experimental oral drug called LPX-TI641 in 48 adults with rheumatoid arthritis or psoriatic arthritis. Participants will receive either the drug or a placebo daily for 28 days. The main goal is to check if the drug is safe and tolerable, and how it…

This study compares two treatments—methotrexate and a TNF inhibitor (adalimumab biosimilar)—to see which better prevents joint damage in people with early psoriatic arthritis. About 108 adults with active disease for less than 2 years will be randomly assigned to one of the two t…

This study tests whether a dermatologist's physical exam or a patient questionnaire is better at finding psoriatic arthritis (PsA) in people with psoriasis. About 500 adults with psoriasis will be screened both ways, then checked by a rheumatologist for a final diagnosis. The goa…

This study is testing a new blood test that may help doctors choose the most effective drug for each person with rheumatic diseases like rheumatoid arthritis or lupus. The test looks at how a person's immune cells react to different medications before treatment starts. The goal i…

This study aims to understand the link between nutrition and disease activity in people with rheumatic diseases like rheumatoid arthritis, lupus, and psoriatic arthritis. Researchers will assess the nutritional status of 460 participants using various scores and check if better n…

This study follows 700 adults with axial spondyloarthritis or psoriatic arthritis who have just started a new medication. Researchers will review medical records and ask patients about their experiences to see how well the treatments control disease activity over 12 months. The g…

This study looks at how weight loss (using tirzepatide) and the biologic drug ixekizumab affect joint, fat, and skin tissues in people with psoriatic arthritis who are overweight or obese. 45 participants will receive one or both treatments, and tissue samples will be taken at th…

This study is collecting health information from up to 10,000 people with conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to better understand these illnesses and help…

This study follows 425 adults with recent psoriatic arthritis (PsA) for up to 10 years to see how many develop joint damage and what factors predict it. Researchers will use X-rays and other data to identify early signs of aggressive disease. The goal is to help doctors decide wh…

This study looks at 200 adults with autoimmune joint diseases like rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. Researchers will measure certain blood markers of oxidative stress at three points over a year. The goal is to see if these markers can help d…