Can shedding pounds calm psoriatic arthritis? new study investigates

NCT ID NCT07443956

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how weight loss (using tirzepatide) and a biologic drug (ixekizumab) affect the body in people with psoriatic arthritis who are overweight or obese. About 45 adults will receive one or both treatments. Researchers will take samples of skin, joint tissue, and fat at the start and after 12 weeks to see what changes occur. The goal is to understand how these treatments work at the tissue level, not to test if they cure the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight psoriasis psoriatic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NHS Greater Glasgow and Clyde

    RECRUITING

    Glasgow, Scotland, G12 0XH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust

    NOT_YET_RECRUITING

    Newcastle upon Tyne, England, NE7 7DN, United Kingdom

    Contact

  • University Hospitals Birmingham NHS Foundation Trust

    NOT_YET_RECRUITING

    Birmingham, England, B12 2GW, United Kingdom

    Contact

  • University Hospitals Coventry and Warwickshire NHS Trust

    NOT_YET_RECRUITING

    Coventry, England, CV2 2DX, United Kingdom

    Contact