Neck ultrasound could revolutionize heart attack prevention for arthritis patients
NCT ID NCT07611747
First seen Jun 03, 2026 · Last updated Jun 21, 2026 · Updated 4 times
Summary
This study tests whether using a carotid ultrasound (a neck scan) to detect hidden plaque in arteries can better prevent heart attacks and strokes in people with inflammatory rheumatic diseases like rheumatoid arthritis and lupus. About 1,944 participants aged 50 and older will be randomly assigned to either standard care or the ultrasound-guided strategy, where those with plaque receive high-dose statins. The goal is to see if this approach reduces major cardiovascular events over four years.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hispital Universitario Virgen de la Arrixaca
NOT_YET_RECRUITINGMurcia, Murcia, Spain
Contact Email: •••••@•••••
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Hospital General Universitario de Alicante
RECRUITINGAlicante, Alicante, Spain
Contact Email: •••••@•••••
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Hospital General Universitario de Ciudad Real
NOT_YET_RECRUITINGCiudad Real, Ciudad Real, Spain
Contact Email: •••••@•••••
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Hospital Sierrallana
RECRUITINGTorrelavega, Cantabria, Spain
Contact Email: •••••@•••••
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Hospital Universitari Son LLàtzer
NOT_YET_RECRUITINGPalma, Isla Baleares, Spain
Contact Email: •••••@•••••
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Hospital Universitario Araba
RECRUITINGVitoria-Gasteiz, Álava, Spain
Contact Email: •••••@•••••
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Hospital Universitario La Paz
NOT_YET_RECRUITINGMadrid, Madrid, Spain
Contact Email: •••••@•••••
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Hospital Universitario Marqués de Valdecilla
NOT_YET_RECRUITINGSantander, Cantabria, Spain
Contact Email: •••••@•••••
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Hospital Universitario Ramón y Cajal
NOT_YET_RECRUITINGMadrid, Madrid, Spain
Contact Email: •••••@•••••
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Hospital Universitario Reina Sofía
NOT_YET_RECRUITINGCórdoba, Córdoba, Spain
Contact Email: •••••@•••••
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Hospital Universitario Vall d'Hebrón
RECRUITINGBarcelona, Barcelona, Spain
Contact Email: •••••@•••••
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Hospital Universitario de Basurto
RECRUITINGBilbao, Vizcaya, Spain
Contact Email: •••••@•••••
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Hospital Universitario de Canarias
NOT_YET_RECRUITINGSan Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain
Contact Email: •••••@•••••
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Hospital Universitario de Elche
NOT_YET_RECRUITINGElche, Alicante, Spain
Contact Email: •••••@•••••
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Hospital Universitario de Gran Canaria Dr. Negrín
NOT_YET_RECRUITINGLas Palmas de Gran Canaria, Las Palmas, Spain
Contact Email: •••••@•••••
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Hospital Vega Baja de Orihuela
RECRUITINGOrihuela, Alicante, Spain
Contact Email: •••••@•••••
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Hospital de Laredo
RECRUITINGLaredo, Cantabria, Spain
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-intensity statins (atorvastatin or rosuvastatin)
What this could lead to
If it works, this could provide a better way to identify and treat heart disease risk in people with inflammatory rheumatic diseases, potentially preventing heart attacks and strokes.
What could go wrong
This is a phase 4 trial, but results may not apply to all patients. The open-label design could introduce bias, and the strategy may not significantly reduce cardiovascular events.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.