SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Clinical trials for SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) explained in plain language.
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New hope for lupus patients: two experimental drugs show promise in reducing disease activity
Disease control CompletedThis study tested two experimental drugs, VAY736 and CFZ533, in 107 adults with systemic lupus erythematosus (SLE). The goal was to see if these drugs could reduce lupus symptoms and allow patients to lower their steroid use. Participants received either one of the drugs or a pla…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 16, 2026 22:21 UTC
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Real-World lupus study reveals how new drug performs outside clinical trials
Disease control CompletedThis study looked at 152 adults with systemic lupus erythematosus (SLE) who started taking anifrolumab during its first year on the market in Spain. Researchers tracked their disease activity, flare-ups, and remission rates using standard medical records. The goal was to see how …
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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New drug shows promise for lupus brain fog in landmark trial
Disease control CompletedThis study tested a new drug called EG-501 for people with lupus who experience cognitive impairment, often called "brain fog." Lupus brain fog can cause memory problems, trouble concentrating, and make daily life very hard. The trial involved 131 adults and compared EG-501 to a …
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: PHASE2 • Sponsor: Evergreen Therapeutics, Inc. • Aim: Disease control
Last updated Jun 09, 2026 12:09 UTC
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New online program helps lupus patients fight fatigue and brain fog
Symptom relief CompletedThis study tested an 8-session online health coaching program called WHEEL for 36 women with lupus. The program helps participants set personal health goals and address symptoms like fatigue, pain, and brain fog that often aren't covered in regular doctor visits. The study measur…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 09, 2026 12:14 UTC
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Lupus gene hunt in kids could unlock disease secrets
Knowledge-focused CompletedThis study looked at 271 children and adults with lupus to find genetic mutations linked to the disease. Researchers focused on families with multiple lupus cases or unusual symptoms. The goal was to better understand what causes lupus and how it affects the immune system, which …
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:52 UTC
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Lupus study aims to unlock secrets of immune system attacks
Knowledge-focused CompletedThis study looked at how the immune system behaves in people with lupus (SLE) and mixed connective tissue disease (MCTD). Researchers measured immune cell responses and tracked disease activity over time. The goal was to better understand these long-term autoimmune diseases, whic…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:24 UTC
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Lupus navigator program aims to close care gaps for minorities
Knowledge-focused CompletedThis study tested a program where a patient navigator helped minority adults with lupus overcome barriers to care, such as scheduling appointments, arranging transportation, and understanding health information. 75 participants completed the program. The goal was to see if this s…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:07 UTC
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Researchers build database to track APS and lupus patients
Knowledge-focused CompletedThis study created a registry to collect medical information from 868 people with Anti-Phospholipid Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE). The goal was to gather data on these conditions, not to test a new treatment. Participants were adults diagnosed with APS …
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 27, 2026 12:03 UTC