New drug shows promise for lupus brain fog in landmark trial
NCT ID NCT07281105
First seen Jan 06, 2026 · Last updated Jun 09, 2026 · Updated 23 times
Summary
This study tested a new drug called EG-501 for people with lupus who experience cognitive impairment, often called "brain fog." Lupus brain fog can cause memory problems, trouble concentrating, and make daily life very hard. The trial involved 131 adults and compared EG-501 to a placebo over 14 weeks to see if it could safely improve thinking and memory. No approved treatments exist for this condition, so this research aims to fill a major gap in care.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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UT Health Houston
Houston, Texas, 77030, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
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