PREGNANCY RELATED

This study looks at whether giving regular blood transfusions to pregnant women with sickle cell disease can reduce serious health problems for both mother and baby. About 50 women will be randomly assigned to receive either repeated transfusions or standard care during pregnancy…

This study compares two different programs designed to reduce heart disease risks in Black women during and after pregnancy. Researchers will track changes in blood pressure and body weight up to one year after birth. The goal is to find the best way to support heart health and r…

This study tests whether delivering medically tailored groceries to the homes of pregnant women on Medicaid can reduce food insecurity and improve birth outcomes like preterm birth and low birth weight. About 360 pregnant women in Cuyahoga County, Ohio, will receive home-delivere…

This study looks at whether using data to track bias and providing doula support can improve pregnancy outcomes for Black mothers. About 60,000 patients at 39 prenatal clinics in North Carolina will take part. The goal is to reduce the number of low-birthweight babies and improve…

This study tests whether giving iron through a vein (IV) early in the second trimester works better than standard iron pills for treating iron deficiency anemia in pregnancy. About 80 pregnant women with mild anemia will be randomly assigned to one of the two treatments. The goal…

This study looks at 900 women who want permanent birth control during a C-section. It compares two ways to remove the fallopian tubes: using a special energy tool versus traditional stitches. The goal is to see which method is safer and costs less.

This study is developing a blood test that can determine the father of a fetus without any risk to the pregnancy. It is designed for victims of sexual assault who become pregnant and need to know paternity for legal reasons. The test analyzes fetal DNA found naturally in the moth…

This study looks at the safety of two HIV prevention methods (a long-acting shot and daily pills) in pregnant and breastfeeding women in Malawi. About 621 women who are already using or start these drugs during pregnancy will be followed along with their infants. The goal is to s…

This study is testing a program called TENDAI4PrEP to help pregnant women in Zimbabwe take PrEP, a daily pill that prevents HIV. The program combines problem-solving skills with support from healthcare providers. Researchers will work with 132 pregnant women to see if the program…

This study tests a program called Care4mommies that teaches self-compassion skills to pregnant women. The goal is to see if it helps mothers feel better emotionally and bond more strongly with their babies after birth. About 96 pregnant women will take part, and researchers will …

This study tests two types of exercise—diaphragmatic breathing and pelvic stabilization—delivered via video calls to help new mothers with pregnancy-related pelvic girdle pain. Sixty women who are at least 3 months postpartum will do the exercises for 8 weeks. Researchers will me…

This study tests whether a buprenorphine patch can reduce withdrawal symptoms in pregnant women with opioid use disorder when they start treatment. About 40 participants will receive either the patch or standard care during the required withdrawal period before taking sublingual …

This study tests whether using a pelvic wand to massage the perineum during late pregnancy and labor helps women feel more in control during childbirth and improves pelvic health afterward. About 140 pregnant women planning to give birth at Beth Israel Deaconess Medical Center wi…

This study looks at two ways to help start labor in full-term pregnant women: membrane stripping and a double balloon catheter. The goal is to see if stripping works as well as the balloon for ripening the cervix and how it affects delivery time and safety. About 400 women will t…

This study tests whether taking progesterone (a hormone) after intrauterine insemination (IUI) can increase the chance of a live birth. About 1,000 couples with unexplained infertility will be randomly assigned to receive progesterone or a placebo. The goal is to see if this simp…

This study tests whether a two-session sexual counseling program for pregnant women can improve sexual function, marital adjustment, sexual quality of life, and reduce depression, anxiety, and stress. About 70 pregnant women between 16-20 weeks will be randomly assigned to receiv…

This study tests a mobile app called BumptUp to see if it helps pregnant and postpartum women in rural areas become more physically active. About 176 women will either use the app or receive an educational brochure. Researchers will track activity levels, weight, diet, blood pres…

This study tests whether creating a personalized lullaby can improve quality of life and reduce stress, anxiety, and depression in pregnant women with epilepsy. About 30 first-time pregnant women with epilepsy will be randomly assigned to either take part in the Lullaby Project o…

This study looks at how people recover after being in the intensive care unit (ICU) for COVID-19 and lung failure. It compares pregnant and non-pregnant patients to see if there are differences in problems with moving, thinking, or mental health. Researchers will review data from…

This study aims to map gene activity in the placenta at two key points in pregnancy: the first trimester and at childbirth. Researchers will analyze small tissue samples from 100 pregnant women to understand how placental cells change over time. The goal is to learn more about no…

This study looks at how anti-seizure medications are processed in the bodies of pregnant women with epilepsy. Researchers will measure drug levels in the blood and urine to understand how much reaches the unborn baby and nursing infant. The goal is to help doctors choose safer do…

This study monitors the safety of the heart medication mavacamten when taken during pregnancy or while breastfeeding. Researchers will track pregnancy outcomes and infant health for up to one year after birth. The goal is to better understand any risks to mothers and babies. Abou…

This study looks for better ways to detect eating disorders in pregnant women. Researchers will compare answers from pregnant women with and without eating disorders to find which questions truly point to a disorder rather than normal pregnancy changes. 50 adult pregnant women wh…

This study tests whether wrist-worn devices can safely monitor pregnant women with congenital heart disease at home. Researchers will track heart rhythms and other data from 50 participants to see if early warning signs of complications can be detected. The goal is to improve car…

This study is testing a special camera (Mueller polarimetric colposcopy) to see if it can measure changes in the cervix during pregnancy. The goal is to find patterns that could help predict if a baby will be born early (preterm). Researchers will study 683 pregnant women, both w…

This study is watching how the heart and blood vessels change during pregnancy and after childbirth. Researchers will measure heart rate, blood pressure, and blood flow in 242 healthy pregnant women. The goal is to learn what is normal so doctors can better spot problems early.

This study looks at whether eating more eggs during pregnancy can improve a baby's brain development. Pregnant women between 12-20 weeks will be split into two groups: one that eats 10-14 eggs per week and another that follows a healthy diet. Researchers will measure the baby's h…

This study aims to adapt a program called Staying Healthy After Childbirth (STAC) to better serve Black women and birthing persons. Researchers will work with community groups to identify barriers and helpful factors, then test the adapted program with 46 participants. The goal i…

This study looks at whether changing room light can help labor progress. Researchers think darkness or red light may boost a natural hormone that helps contractions, while bright light might slow them. About 100 pregnant women will use a home monitor to track contractions and rep…

This study is collecting health information from about 9,500 women in Kalifabougou, Mali, to better understand pregnancy outcomes and malaria. Researchers will track pregnancies, malaria cases, and other health events through regular check-ups and surveys. The goal is to gather d…

This study looks at how mothers with HIV in the United States decide to feed their babies, whether breastfeeding or formula. Researchers will interview mothers and track their choices and health outcomes. The goal is to learn what factors influence these decisions and to test a n…

This study looks at whether pregnant women with complications (like high blood pressure or slow fetal growth) can use a remote device at home to monitor their baby's heart rate. About 60 participants will try the device daily and report their symptoms via a phone app. The goal is…

This study aims to develop a smarter computer program that can separate a mother's heartbeat from her baby's using a simple belly sensor. Researchers will collect data from 350 pregnant women in their second or third trimester. The goal is to make fetal monitoring faster and more…

This study looks at whether simulation training for doctors, nurses, and midwives can reduce the number of cervical exams women receive during labor and make exam results more consistent. Over 1,100 healthcare providers and patients will take part. The goal is to improve care wit…

This study follows 100 pregnant women with opioid use disorder to learn how to better predict and prevent health issues for both mother and child. Researchers will track whether mothers relapse and whether newborns experience withdrawal. The goal is to improve care without changi…

This study looks at pregnant women with mild to moderate eczema (atopic dermatitis) who use ruxolitinib cream and compares their babies' health to those who don't use the cream. Researchers want to see if the cream affects the risk of birth defects. About 958 women aged 15-50 wil…

This study compares pregnancy and infant outcomes in women with atopic dermatitis (eczema) who used ruxolitinib cream during pregnancy versus those who used topical corticosteroids. Researchers will analyze health records from over 5,600 women to see if there are differences in b…

This study tests whether small wearable sensors can accurately track movement and walking during the first stage of labor in women using low-dose epidural pain relief. Researchers aim to understand how labor and epidurals affect gait, which could help predict fall risk and monito…

This study follows 200 pregnant women who take tildrakizumab for conditions like psoriasis, along with a similar group who don't take the drug. Researchers track pregnancy outcomes and infant health up to one year after birth to check for birth defects or other problems. The goal…

This study follows 825 pregnant women who need blood thinners for blood clots, tracking how doctors manage these medications around labor and delivery. The goal is to find which strategies lead to the fewest bleeding problems. Researchers hope to improve care for mothers and babi…

This study looks at whether a tool called MyPath helps women with substance use disorder make informed choices about birth control after giving birth. About 400 women will use the tool during pregnancy or right after delivery. Researchers will track which birth control method the…

This study looks at why some pregnant women develop high blood pressure and whether a nutrient called tetrahydrofolate (5-MTHF) can improve blood vessel health. Researchers will measure BH4 levels in 128 women with and without pre-eclampsia, and use ultrasound to check heart and …

This study is testing a new wireless skin sensor that monitors vital signs like heart rate and breathing in healthy newborns right after birth. About 600 babies will wear both the wireless sensor and the standard wired monitor for 2 hours. The goal is to see if the wireless syste…

This study monitors up to 20 people who took the drug odevixibat during pregnancy or while breastfeeding. Researchers will collect routine medical data to check for birth defects, pregnancy complications, and effects on infants. No extra tests or visits are required—only informat…

This study uses MRI scans to measure pancreas size in pregnant women and their unborn babies. Researchers want to see how the pancreas changes during pregnancy and how those changes are linked to diabetes. The goal is to better understand diabetes risk for both mother and child. …

This study is testing whether a program originally designed for clinics can work in community settings to help pregnant women with a BMI over 30 stay active and healthy. Researchers will enroll 60 expecting mothers to see if the program is easy to use and follow. The goal is to l…

This study follows 60 women with neuromyelitis optica spectrum disorder (NMOSD) who received UPLIZNA during pregnancy or within 6 months before conception. Researchers will collect data on pregnancy outcomes, including birth defects, preterm birth, and infant development over 10 …

This study is a registry that will enroll up to 1,000 pregnant women or those planning pregnancy who have autoimmune diseases like lupus or rheumatoid arthritis. Researchers at Duke University will track their health and pregnancy outcomes to identify risk factors and find ways t…

This study interviews 60 women who gave birth in French-speaking Belgium within the past year to understand why they chose a particular place of birth (home, birth center, or hospital) and what their childbirth experience was like. Researchers also talk to birth companions and he…

This study tests a fully online sexual health program called Yes and Know for teens aged 14-19. About 1,200 participants will be split into two groups: one gets the sexual health program, the other gets a nutrition program. Researchers will survey them at the start, 3 months, and…