LIVER METASTASES

This study is testing a new combination treatment for people with metastatic melanoma that has spread to the liver. It combines a liver-targeted chemotherapy (HEPZATO KIT™) with a two-drug immunotherapy (Opdualag™). The main goals are to see if this combination is safe and if it …

This study tests whether combining a non-invasive ultrasound treatment called histotripsy with standard chemotherapy works better for people with advanced colorectal cancer that has spread to the liver. About 100 participants will receive both treatments to see if this combinatio…

This study is testing a new combination treatment for cancer that has spread to the liver. It combines a standard procedure (TACE) that delivers chemotherapy directly to the liver tumor with an added drug (bevacizumab) that aims to starve the tumor by blocking its blood supply. T…

This study is testing whether a single, powerful session of MRI-guided radiation can stop liver tumors from growing in people whose colorectal cancer has spread there. Researchers will see if this one-time treatment is effective and safe, and if special MRI images can predict how…

This study is testing a new radiation therapy approach that uses MRI scans during treatment to adjust radiation beams in real time. Researchers want to see if this method can better target tumors while sparing healthy tissue in patients with various cancers including pancreatic, …

This study is testing if adding a drug called bevacizumab to a standard three-drug treatment can better control an aggressive type of lung cancer that has spread to the liver. It will involve 39 adults with extensive-stage small cell lung cancer who have not had prior treatment. …

This international study is testing if a single, very high dose of precisely targeted radiation is better than a standard high dose for treating tumors that have spread to the liver from other cancers. It will involve 114 patients and uses advanced MRI-guided technology to delive…

This study is testing a new, faster way to deliver precise radiation treatment for liver cancer. It uses real-time MRI scans to guide the radiation beam and aims to complete the entire treatment in a single session, without needing a separate planning scan. The main goal is to se…

This study is testing if adding a very low dose of radiation to the liver can make standard immunotherapy work better for people with lung cancer or melanoma that has spread to the liver. It is for patients already planning to receive immunotherapy. The goal is to see if this com…

This study is testing whether a simple blood test can help doctors decide which patients need chemotherapy after surgery to remove colorectal cancer that has spread to the liver. The test looks for tiny pieces of cancer DNA in the blood. Patients with no cancer DNA might get less…

This study is testing a personalized vaccine designed to prevent liver cancer from coming back after surgery. The vaccine is custom-made for each patient using their own tumor and immune cells, and is given alongside an immunotherapy drug called nivolumab. The goal is to see if t…

This study is testing whether analyzing tissue samples taken right after a liver tumor ablation procedure can help doctors identify any remaining live cancer cells. The goal is to use this information to guide the next steps in treatment for patients with cancer that has spread t…

This study is testing a new, high-precision radiation technique for people with cancer that has spread to the liver. Using real-time MRI scans to guide the radiation, researchers aim to safely deliver the highest possible dose to the tumors while protecting nearby healthy organs.…

This study is testing whether adding an MRI scan to the standard CT scan helps doctors make better decisions about who should have pancreatic cancer surgery. Researchers want to see if the MRI finds small liver metastases that the CT misses, which would mean surgery isn't the rig…

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …

This study aims to use artificial intelligence (AI) to make a minimally invasive liver cancer treatment called thermal ablation more effective and accessible. Researchers will collect data from 1500 patients to develop AI tools that help doctors better select patients, plan treat…