Could a little liver radiation boost cancer immunotherapy?
NCT ID NCT07225036
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding low-dose radiation to the liver before standard immunotherapy can help people with melanoma or non-small cell lung cancer that has spread to the liver. About 21 participants will receive radiation before their first three immunotherapy cycles. The goal is to see if this combination improves how long the cancer stays under control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Low-dose radiation to the liver
What this could lead to
If it works, this could improve how well immunotherapy controls cancer in patients with liver metastases, potentially extending the time without disease progression.
What could go wrong
This is a very early, small trial with only 21 participants, so results may not apply broadly. The radiation could cause side effects like fatigue or liver irritation, and it may not improve outcomes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Cincinnati Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••