Can a simple blood test tell if cancer is really gone?

NCT ID NCT06287723

Recruiting now Knowledge-focused Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a blood test that looks for cancer DNA (called ctDNA) can find leftover cancer cells after surgery in people with colorectal cancer that has spread to the liver. The goal is to see which test works best at predicting if the cancer will come back. Thirty adults who are having surgery to remove their liver metastases will give blood samples, and researchers will track their health for three years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: liquid biopsy (ctDNA analysis)
What this could lead to: If successful, this could help doctors know which patients need extra treatment after surgery and which do not, reducing unnecessary side effects.
What could go wrong: This is a small, early-stage study (30 people) focused on comparing different tests, not on proving a new treatment works. The tests may not be accurate enough to change practice yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Neoplasm, Residual

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER CTDNA LIQUID BIOPSY LIVER METASTASES MINIMAL RESIDUAL DISEASE STAGE IV COLORECTAL CANCER

Contacts and locations

Locations

CHU de Montpellier
RECRUITING

Montpellier, 34295, France
Institu régional du Cancer de Montpellier (ICM)
RECRUITING

Montpellier, 34295, France

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