One-shot radiation zaps liver tumors in colorectal cancer trial

NCT ID NCT06130280

Recruiting now Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a single, high-dose session of MRI-guided radiation can control colorectal cancer that has spread to the liver. Researchers will treat up to 32 adults with up to 3 small liver tumors. They will track tumor growth, side effects, and look for MRI features that predict success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MR-guided single fraction stereotactic body radiation therapy (SBRT)
What this could lead to: If successful, this could offer a quick, one-time radiation option to control liver tumors from colorectal cancer, potentially reducing the need for multiple treatments.
What could go wrong: This is a small, early-phase trial with only 32 people, so results may not apply to everyone. The high radiation dose could cause side effects like liver damage or inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER LIVER METASTASES

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All protocol activities)
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
RECRUITING

Rockville Centre, New York, 11553, United States
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
RECRUITING

Harrison, New York, 10604, United States

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