Liver transplant study aims to unlock genetic secrets of colorectal cancer spread

NCT ID NCT05398380

Recruiting now Knowledge-focused Sponsor: Hospital Vall d'Hebron Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at genetic changes in patients with colorectal cancer that has spread only to the liver and cannot be removed by surgery. Researchers will perform liver transplants and then analyze tumor genetics and blood samples to better understand why the cancer spreads and how to monitor it. The goal is to improve future treatments and outcomes for these patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: liver transplantation
What this could lead to: If successful, this research could lead to better ways to monitor and treat colorectal cancer that has spread to the liver, potentially improving survival after liver transplant.
What could go wrong: This is a small, early-stage study focused on gathering information, not testing a new treatment. It may not lead to direct benefits for participants, and liver transplant carries serious risks like rejection or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm metastatic malignant neoplasm in the colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER GENETIC CHANGE LIVER METASTASES

Contacts and locations

Locations

Department of HPB Surgery and Transplants, Hospital Vall d´Hebron
RECRUITING

Barcelona, Barcelona, 08035, Spain

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