INVASIVE BREAST CANCER
Clinical trials for INVASIVE BREAST CANCER explained in plain language.
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New combo therapy shows promise for Tough-to-Treat breast cancer
Disease control OngoingThis study tests whether adding pembrolizumab (Keytruda) to sacituzumab govitecan helps people with a certain type of advanced breast cancer (HR+/HER2-) live longer without the disease getting worse. About 110 participants will receive either the drug alone or the combination. Th…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Ana C Garrido-Castro, MD • Aim: Disease control
Last updated May 17, 2026 05:44 UTC
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New drug combo shows promise against tough breast cancer
Disease control OngoingThis study tests whether adding the experimental drug onvansertib to standard chemotherapy (paclitaxel) is safe and effective for people with triple-negative breast cancer that has spread to other parts of the body. About 50 adults with advanced disease are participating. The goa…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Antonio Giordano, MD • Aim: Disease control
Last updated May 17, 2026 05:34 UTC
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Could a 1-week radiation zap be just as good as 3 weeks for breast cancer?
Disease control OngoingThis study compares a 1-week radiation schedule to the standard 3-week schedule for people with early-stage breast cancer who had lumpectomy. The goal is to see if the shorter treatment controls cancer just as well while causing fewer side effects. About 72 adults with non-invasi…
Matched conditions: INVASIVE BREAST CANCER
Phase: NA • Sponsor: Coordinación de Investigación en Salud, Mexico • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Shorter radiation during surgery shows promise for older breast cancer patients
Disease control OngoingThis study looks at giving a single dose of radiation directly to the tumor site during breast-conserving surgery for women aged 60 and older with early-stage, hormone-sensitive breast cancer. The goal is to see if this shorter, more targeted approach works as well as standard we…
Matched conditions: INVASIVE BREAST CANCER
Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New drug shows promise against tough breast cancers
Disease control OngoingThis study tests whether the drug cemiplimab can help shrink or eliminate breast cancer before surgery in people with high-risk or locally advanced luminal or triple-negative breast cancer. 36 participants will receive the drug and then have their tumor tissue checked for a compl…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New hope: targeted drug olaparib shows promise for Hard-to-Treat breast cancers
Disease control OngoingThis study tests a drug called olaparib in people with metastatic breast cancer that has spread beyond the breast. Participants must have a specific gene mutation that makes their cancer cells less able to repair DNA damage. The goal is to see if olaparib can shrink tumors or slo…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated May 11, 2026 20:53 UTC
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Blood test may tame Chemo's nerve damage
Knowledge-focused TerminatedThis study looks at whether doctors can consistently measure the chemotherapy drug paclitaxel in the blood of cancer patients. The goal is to see if this could help adjust doses to kill cancer while reducing nerve damage, a common side effect. About 22 adults with various solid t…
Matched conditions: INVASIVE BREAST CANCER
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 17, 2026 05:36 UTC
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Tiny tumor particles could light the way for breast cancer surgery
Knowledge-focused OngoingThis study takes tumor tissue from 50 women with invasive breast cancer to grow 3D models called organoids in the lab. These organoids are used to collect tiny particles released by cells, known as extracellular vesicles, which naturally seek out tumor tissue. The goal is to see …
Matched conditions: INVASIVE BREAST CANCER
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Knowledge-focused
Last updated May 17, 2026 05:34 UTC