One-Time radiation during surgery could spare older breast cancer patients weeks of treatment
NCT ID NCT04414202
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at giving a single dose of radiation directly to the tumor site during breast-conserving surgery in women aged 60 and older with early-stage, hormone-sensitive breast cancer. The goal is to see if this shorter, targeted approach controls the cancer as well as standard weeks-long whole-breast radiation. Researchers are tracking local relapse rates and cosmetic outcomes in 519 participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- intra-operative partial irradiation (radiation therapy given during surgery)
- What this could lead to
- If successful, this could offer a shorter, more convenient radiation option for older women with early-stage breast cancer, reducing treatment time from weeks to a single dose.
- What could go wrong
- This is an observational study, not a randomized trial, so results may not prove the approach is as effective as standard whole-breast radiation. Long-term local relapse rates are still being tracked.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Icm Val D'Aurelle
Montpellier, Herault, 34398, France
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