One-Time radiation during surgery could spare older breast cancer patients weeks of treatment
NCT ID NCT04414202
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at giving a single dose of radiation directly to the tumor site during breast-conserving surgery in women aged 60 and older with early-stage, hormone-sensitive breast cancer. The goal is to see if this shorter, targeted approach controls the cancer as well as standard weeks-long whole-breast radiation. Researchers are tracking local relapse rates and cosmetic outcomes in 519 participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intra-operative partial irradiation (radiation therapy given during surgery)
What this could lead to
If successful, this could offer a shorter, more convenient radiation option for older women with early-stage breast cancer, reducing treatment time from weeks to a single dose.
What could go wrong
This is an observational study, not a randomized trial, so results may not prove the approach is as effective as standard whole-breast radiation. Long-term local relapse rates are still being tracked.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Icm Val D'Aurelle
Montpellier, Herault, 34398, France