New combo therapy aims to slow advanced breast cancer
NCT ID NCT04448886
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding pembrolizumab (Keytruda) to sacituzumab govitecan helps people with a common type of advanced breast cancer (HR+/HER2-). About 110 participants receive either the combination or sacituzumab alone. The goal is to see if the combo delays cancer growth longer. This is not a cure; treatment aims to control the disease.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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DF/BWCC in Clinical Affiliation with South Shore Hospital
South Weymouth, Massachusetts, 02190, United States
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DFCI @ Foxborough
Foxborough, Massachusetts, 02035, United States
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DFCI @ Milford Regional Hospital
Milford, Massachusetts, 01757, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Emory University/Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Pennsylvania-Abramson Cancer Center
Philadelphia, Pennsylvania, 19104, United States