Could a common blood pressure drug prevent radiation scarring in breast cancer patients?
NCT ID NCT05637216
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether losartan, a drug already used for high blood pressure, can reduce scarring (fibrosis) caused by radiation therapy in breast cancer patients. 43 women who had breast surgery and need radiation will receive either losartan or a placebo. Researchers will measure breast and lung scarring using exams and CT scans, along with blood markers of inflammation and aging cells.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Losartan (a blood pressure drug)
What this could lead to
If it works, this could point toward a way to prevent or reduce scarring and stiffness in breast tissue and lungs after radiation therapy.
What could go wrong
This is a small, early-phase pilot study with only 43 participants. The drug is already approved for blood pressure, but its effect on radiation fibrosis is unproven, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Vail Health Shaw Cancer Center
Edwards, Colorado, 81632, United States