New approach: radiation before surgery for breast cancer

NCT ID NCT02728076

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests giving a short course of focused radiation before breast cancer surgery, using MRI for precise planning. The goal is to treat a smaller area of the breast and possibly reduce side effects. About 39 women with early-stage breast cancer will receive five radiation treatments over 10 days, then have surgery about 5-8 weeks later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (3D conformal external beam irradiation)

What this could lead to

If successful, this approach could reduce the amount of breast tissue needing radiation and lower side effects after surgery.

What could go wrong

This is a small, early-phase study with only 39 participants, so results may not apply widely. There is also a risk of postoperative complications or needing additional surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Froedtert Hospital and the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States